| Long name: |
ALEXA FLUOR 647 Conjugated, MyD88 Polyclonal Antibody |
| Also known as: |
Anti-MyD88 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
MyD88 |
| Specificity: |
This is a highly specific antibody against MyD88 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
240-290/296 |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from mouse MyD88 |
| Gene ID Number: |
17874 |
| Swiss Prot: |
P22366 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, Acts via IRAK1, IRAK2, IRF7 and TRAF6, Increases IL-8 transcription, Involved in IL-18-mediated signaling pathway, Isoform 2 is defective in its ability to induce IRAK phosphorylation and NF-kappa-B activation and can function as a negative regulator of activation by IL-1 or lipopolysaccharide (LPS), MyD88-mediated signaling in intestinal epithelial cells is crucial for maintenance of gut homeostasis and controls the expression of the antimicrobial lectin REG3G in the small intestine, NOS2/INOS, and IL12A genes, cytokine secretion and the inflammatory response, leading to NF-kappa-B activation, Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the MyD88 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
MyD88 |
| Short name: |
MyD88 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, myeloid differentiation primary response 88 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
7562 |
| Gene: |
MYD88 |
More about : MYD88 |
| Long gene name: |
myeloid differentiation primary response 88 |
| Synonyms gene name: |
myeloid differentiation primary response gene (88) |
| Locus: |
3p22, 2 |
| Discovery year: |
1997-12-23 |
| GenBank acession: |
U84408 |
| Entrez gene record: |
4615 |
| Pubmed identfication: |
9013863 |
| RefSeq identity: |
NM_002468 |
| Classification: |
TIR domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000131083 |
| Locus Specific Databases: |
LRG_157 |