| Long name: |
SLC4A4 variant A Primary Polyclonal Antibody |
| Also known as: |
SLC4A4 variant A PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
SLC4A4 variant A |
| Specificity: |
This is a highly specific antibody against SLC4A4 variant A |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SLC4A4 variant A |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
It may regulate bicarbonate influx/efflux at the basolateral membrane of cells and regulate intracellular pH, Multiple transcript variants encoding different isoforms have been found for this gene, Mutations in this gene are associated with proximal renal tubular acidosis, Oct 2008], SLC4A4 interacts with carbonic anhydrase 2 and carbonic anhydrase 4 which may regulate transporter activity, There are four named isoforms produced by alternative splicing, [provided by RefSeq, SLC4A4 (Electrogenic sodium bicarbonate cotransporter 1) is an electrogenic sodium/bicarbonate cotransporter with a Na(+):HCO3(-) stoichiometry varying from 1:2 to 1:3, This gene encodes a sodium bicarbonate cotransporter (NBC) involved in the regulation of bicarbonate secretion and absorption and intracellular pH |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
HNBC1, KNBC, NBC1, NBC2, NBCe1-A, NBCe1-A, SLC4A4 protein, SLC4A5, Slc4a4, electrogenic sodium bicarbonate cotransporter 1 isoform 2, hhNMC, pNBC, sodium bicarbonate cotransporter NBCe1 variant A |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SLC4A4 variant A |
| Short name: |
SLC4A4 variant A Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
SLC4A4 variant A (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11030 |
| Gene: |
SLC4A4 |
More about : SLC4A4 |
| Long gene name: |
solute carrier family 4 member 4 |
| Synonyms gene: |
SLC4A5 |
| Synonyms gene name: |
member 4 , member 4 solute carrier family 4 (sodium bicarbonate cotransporter), sodium bicarbonate cotransporter, solute carrier family 4 |
| Synonyms: |
NBC1 HNBC1 NBC2 pNBC hhNMC |
| Locus: |
4q13, 3 |
| Discovery year: |
1998-12-11 |
| GenBank acession: |
AF007216 |
| Entrez gene record: |
8671 |
| Pubmed identfication: |
9235899 9651366 |
| RefSeq identity: |
NM_003759 |
| Classification: |
Solute carriers |
| Havana BLAST/BLAT: |
OTTHUMG00000129907 |