| Long name: |
Chloride Channel 5 Primary Polyclonal Antibody |
| Also known as: |
Chloride Channel 5 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Chloride Channel 5 |
| Specificity: |
This is a highly specific antibody against Chloride Channel 5 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Mitochondrion |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Chloride Channel 5/CLC5 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
1p36 and 16p13, 3q28, 4q32, CLC1 is highly expressed in skeletal muscle, CLC2 is highly expressed in the epithelia of several organs including lung, CLC3 expression is particularly abundant in neuronal tissue, CLC6 and CLC7 are broadly expressed in several tissues including testis, CLCs regulate excitability in muscle and nerve cells, Mutations in the gene encoding CLC1 lead to myotonia, Mutations in the gene encoding CLC5 lead to Dentâ, The genes encoding human CLC-1 through CLC-7 map to chromosomes 7q32, Xp11, Xp22, a critical component of all living cells, a renal disorder characterized by proteinuria and hypercalciuria, aid in organic solute transport and maintain cellular volume, an inheritable disorder characterized by muscle stiffness and renal salt wasting, brain and muscle, kidney, respectively, which suggests CLC2 may be a possible therapeutic target for cystic fibrosis, while CLC4 expression is evident in skeletal and cardiac muscle as well as brain, &euro, &trade, 23-p11, 3, 22, The family of voltage-dependent chloride channels (CLCs) regulate cellular trafficking of chloride ions, s disease |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CLC5, CLCK2, CLCN5, CLCN5_HUMAN, Chloride transporter ClC-5, ClC-5, DENTS, H+/Cl- exchange transporter 5, NPHL1, NPHL2, XLRH, XRN, hCIC-K2, Chloride channel protein 5 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Chloride Channel 5 |
| Short name: |
Chloride Channel 5 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Chloride Channel 5 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
13517 |
| Gene: |
CLIC5 |
More about : CLIC5 |
| Long gene name: |
chloride intracellular channel 5 |
| Synonyms: |
DFNB102 |
| Locus: |
6p21, 1 |
| Discovery year: |
2000-10-31 |
| GenBank acession: |
AF216941 |
| Entrez gene record: |
53405 |
| Pubmed identfication: |
10793131 24781754 |
| Classification: |
Chloride intracellular channels Deafness associated genes |
| Havana BLAST/BLAT: |
OTTHUMG00000014775 |