| Long name: |
Pokemon/ZBTB7 Primary Polyclonal Antibody |
| Also known as: |
Pokemon/ZBTB7 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Pokemon/ZBTB7 |
| Specificity: |
This is a highly specific antibody against Pokemon/ZBTB7 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Pokemon |
| Gene ID number: |
51341 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Deletion analysis and a DNA decoy assay indicated that the NEG-U and NEG-D elements were involved in negative regulation of the Pokemon promoter, Electrophoretic mobility shift assays suggested that the NEG-U, Moreover, Mutation analysis demonstrated that cooperation of the NEG-U and NEG-D elements led to negative regulation of the Pokemon promoter, NEG-D and POS-D elements were specifically bound by the nuclear extract from A549 cells in vitro, Taken together, To investigate the molecular mechanism regulating expression of the Pokemon gene in humans, Transient analysis revealed that the Pokemon promoter is constitutive, and also define a novel regulatory sequence that may be used to decrease expression of the Pokemon gene in cancer gene therapy, but also plays an important role in cell tumorigenesis, its 5'-upstream region was cloned and analyzed, not only regulates the expression of many genes, our results elucidate the mechanism underlying the regulation of Pokemon gene transcription, the NEG-U and NEG-D elements needed to be an appropriate distance apart in the Pokemon promoter in order to cooperate, the POK erythroid myeloid ontogenic factor, whereas the POS-D element was mainly responsible for its strong activity, Pokemon |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
FBI-1, FBI1, Factor that binds to inducer of short transcripts protein 1, HIV-1 1st-binding protein 1, LRF, Leukemia/lymphoma related factor, Pokemon, TIP21, TTF-I interacting peptide 21, ZBT7A_HUMAN, ZBTB7, ZBTB7A, Zinc finger and BTB domain-containing protein 7A, Factor binding IST protein 1 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Pokemon/ZBTB7 |
| Short name: |
Pokemon/ZBTB7 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Pokemon/ZBTB7 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
18078 |
| Gene: |
ZBTB7A |
More about : ZBTB7A |
| Long gene name: |
zinc finger and BTB domain containing 7A |
| Synonyms gene: |
ZBTB7 |
| Synonyms gene name: |
zinc finger and BTB domain containing 7 |
| Synonyms: |
FBI-1 LRF DKFZp547O146 pokemon ZNF857A |
| Synonyms name: |
HIV-1 inducer of short transcripts binding protein lymphoma related factor , zinc finger and BTB domain containing 7A |
| Locus: |
19p13, 3 |
| Discovery year: |
2004-01-16 |
| GenBank acession: |
AF000561 |
| Entrez gene record: |
51341 |
| Pubmed identfication: |
9973611 9927193 |
| RefSeq identity: |
NM_015898 |
| Classification: |
BTB domain containing Zinc fingers C2H2-type |
| Havana BLAST/BLAT: |
OTTHUMG00000181792 |