| Long name: |
FITC Conjugated, TrkA Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TrkA |
| Specificity: |
This is a highly specific antibody against TrkA |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human TrkA |
| Gene ID number: |
4914 |
| Tested applications: |
IF(IHC-P), FCM |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
BDNF and to a lesser extent, By comparison, NGFR p175, NGFR p175 accelerates Trk activation and may recruit downstream dffector molecules to the ligand-bound receptor complex, NT-3, Nerve growth factor (NGF) stimulates tyrosine phosphorylation of Trk gp 140 in neural cell lines and in embryonic dorsal root ganglia, The prototype member of this gene family, The third member of the Trk receptor family, Trk A, Trk C gp140, Trk C incodes a 140 kDa protein, binds to neurotrophic factors with low affinity but is required for efficient signaling, but not NGF, can induce tyrosine phophorylayion of Trk B gp 145, encodes a 140 kDa cell surface receptor , gp140, that is preferentially expressed in brain tissue and primarily functions as a receptor for NT-3, the expression of which is restricted in vivo to neurons of the sensory spinal and cranial gangliaof neurocrest origin, An additional component of the Trk receptor complex, The Trk family of nerve growth factor receptors includes Trk A(also referfed to as Trk A gp140), Trk B and Trk C |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
CIPA, DKFZp781I14186, High affinity nerve growth factor receptor, High affinity nerve growth factor receptor precursor, High affinity nerve growth factor receptor precursor, MTC, MTC, NTRK1_HUMAN, Ntrk 1, Ntrk1, Ntrk1, Oncogene TRK, Oncogene TRK, TRK, TRK, TRK 1, TRK1, TRK1 transforming tyrosine kinase protein, TRK1-transforming tyrosine kinase protein, Trk A, Trk-A, Tropomyosin-related kinase A, Tyrosine Receptor Kinase A, Tyrosine kinase receptor, Tyrosine kinase receptor A, gp140trk, neurotrophic tyrosine kinase receptor type 1, neurotrophic tyrosine kinase receptor type 1, p140 TrkA, p140-TrkA, CIPA |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
TrkA Conjugated |
| Short name: |
FITC Conjugated, TrkA Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, TrkA (Antibody to) |
| Alternative technique: |
antibodies |