| Long name: |
TLR2 Primary Polyclonal Antibody |
| Also known as: |
TLR2 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
TLR2 |
| Specificity: |
This is a highly specific antibody against TLR2 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
730-780/784 |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TLR2 |
| Gene ID number: |
7097 |
| Swiss Prot: |
O60603 |
| Tested Applications: |
FCM, IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Bovine, Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Acts via MYD88 and TRAF6, Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides, May also promote apoptosis in response to lipoproteins, Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), cytokine secretion and the inflammatory response, leading to NF-kappa-B activation, phenol-soluble modulin (PSM) and B, soluble tuberculosis factor (STF), Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components, burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR6 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CD282, TLR2, Toll-like receptor 2, Toll/interleukin-1 receptor-like protein 4, TIL4 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
TLR2 |
| Short name: |
TLR2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
toll-like receptor 2 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CD282 and TIL4, Cell surfaces, TLR2 and IDBG-41789 and ENSG00000137462 and 7097, TLR2 and IDBG-629032 and ENSBTAG00000008008 and 281534, Tlr2 and IDBG-154818 and ENSMUSG00000027995 and 24088, lipopeptide binding, this GO :0001666 and response to hypoxia and biological process this GO :0001774 and microglial cell activation and biological process this GO :0001875 and lipopolysaccharide receptor activity and molecular function this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002238 and response to molecule of fungal origin and biological process this GO :0002687 and positive regulation of leukocyte migration and biological process this GO :0002752 and cell surface pattern recognition receptor signaling pathway and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0004872 and receptor activity and molecular function this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006691 and leukotriene metabolic process and biological process this GO :0006915 and apoptotic process and biological process this GO :0006954 and inflammatory response and biological process this GO :0006955 and immune response and biological process this GO :0007165 and signal transduction and biological process this GO :0007252 and I-kappaB phosphorylation and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0008329 and signaling pattern recognition receptor activity and molecular function this GO :0009617 and response to bacterium and biological process this GO :0009636 and response to toxic substance and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0030177 and positive regulation of Wnt signaling pathway and biological process this GO :0031663 and lipopolysaccharide-mediated signaling pathway and biological process this GO :0032289 and central nervous system myelin formation and biological process this GO :0032493 and response to bacterial lipoprotein and biological process this GO :0032494 and response to peptidoglycan and biological process this GO :0032496 and response to lipopolysaccharide and biological process this GO :0032570 and response to progesterone and biological process this GO :0032695 and negative regulation of interleukin-12 production and biological process this GO :0032700 and negative regulation of interleukin-17 production and biological process this GO :0032722 and positive regulation of chemokine production and biological process this GO :0032728 and positive regulation of interferon-beta production and biological process this GO :0032733 and positive regulation of interleukin-10 production and biological process this GO :0032735 and positive regulation of interleukin-12 production and biological process this GO :0032741 and positive regulation of interleukin-18 production and biological process this GO :0032755 and positive regulation of interleukin-6 production and biological process this GO :0032757 and positive regulation of interleukin-8 production and biological process this GO :0032760 and positive regulation of tumor necrosis factor production and biological process this GO :0032868 and response to insulin and biological process this GO :0034123 and positive regulation of toll-like receptor signaling pathway and biological process this GO :0034134 and toll-like receptor 2 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0035354 and Toll-like receptor 1-Toll-like receptor 2 protein complex and cellular component this GO :0035355 and Toll-like receptor 2-Toll-like receptor 6 protein complex and cellular component this GO :0038123 and toll-like receptor TLR1:TLR2 signaling pathway and biological process this GO :0038124 and toll-like receptor TLR6:TLR2 signaling pathway and biological process this GO :0042346 and positive regulation of NF-kappaB import into nucleus and biological process this GO :0042495 and detection of triacyl bacterial lipopeptide and biological process this GO :0042496 and detection of diacyl bacterial lipopeptide and biological process this GO :0042497 and triacyl lipopeptide binding and molecular function this GO :0042498 and diacyl lipopeptide binding and molecular function this GO :0042535 and positive regulation of tumor necrosis factor biosynthetic process and biological process this GO :0042834 and peptidoglycan binding and molecular function this GO :0042892 and chloramphenicol transport and biological process this GO :0042995 and cell projection and cellular component this GO :0044130 and negative regulation of growth of symbiont in host and biological process this GO :0044297 and cell body and cellular component this GO :0045087 and innate immune response and biological process this GO :0045429 and positive regulation of nitric oxide biosynthetic process and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046209 and nitric oxide metabolic process and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0048714 and positive regulation of oli this GO dendrocyte differentiation and biological process this GO :0050715 and positive regulation of cytokine secretion and biological process this GO :0050729 and positive regulation of inflammatory response and biological process this GO :0050830 and defense response to Gram-positive bacterium and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0051770 and positive regulation of nitric-oxide synthase biosynthetic process and biological process this GO :0052063 and induction by symbiont of defense-related host nitric oxide production and biological process this GO :0060907 and positive regulation of macrophage cytokine production and biological process this GO :0070542 and response to fatty acid and biological process this GO :0070891 and lipoteichoic acid binding and molecular function this GO :0071221 and cellular response to bacterial lipopeptide and biological process this GO :0071223 and cellular response to lipoteichoic acid and biological process this GO :0071224 and cellular response to peptidoglycan and biological process this GO :0071723 and lipopeptide binding and molecular function this GO :0071726 and cellular response to diacyl bacterial lipopeptide and biological process this GO :0071727 and cellular response to triacyl bacterial lipopeptide and biological process, this GO :0001875 : lipopolysaccharide receptor activity, this GO :0001875 : lipopolysaccharide receptor activity and also this GO :0004872 : receptor activity and also this GO :0004888 : transmembrane signaling receptor activity and also this GO :0005515 : protein binding and also this GO :0008329 : signaling pattern recognition receptor activity and also this GO :0042497 : triacyl lipopeptide binding and also this GO :0042498 : diacyl lipopeptide binding and also this GO :0042834 : peptidoglycan binding and also this GO :0046982 : protein heterodimerization activity and also this GO :0070891 : lipoteichoic acid binding and also this GO :0071723 : lipopeptide binding, this GO :0004872 : receptor activity, this GO :0004888 : transmembrane signaling receptor activity, this GO :0005515 : protein binding, this GO :0008329 : signaling pattern recognition receptor activity, this GO :0042497 : triacyl lipopeptide binding, this GO :0042498 : diacyl lipopeptide binding, this GO :0042834 : peptidoglycan binding, this GO :0046982 : protein heterodimerization activity, this GO :0070891 : lipoteichoic acid binding, this GO :0071723 : lipopeptide binding, toll-like receptor 2 |
| Identity: |
11848 |
| Gene: |
TLR2 |
More about : TLR2 |
| Long gene name: |
toll like receptor 2 |
| Synonyms gene name: |
toll-like receptor 2 |
| Synonyms: |
TIL4 CD282 |
| Locus: |
4q31, 3 |
| Discovery year: |
1998-06-25 |
| GenBank acession: |
U88878 |
| Entrez gene record: |
7097 |
| Pubmed identfication: |
9435236 |
| Classification: |
CD molecules Toll like receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000161525 |