| Long name: |
PDZ RHOGEF/GTRAP48 Primary Polyclonal Antibody |
| Also known as: |
PDZ RHOGEF/GTRAP48 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
PDZ RHOGEF/GTRAP48 |
| Specificity: |
This is a highly specific antibody against PDZ RHOGEF/GTRAP48 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PDZ RHOGEF/GTRAP48 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity, Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia, Jul 2008], The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals, Two alternative transcripts encoding different isoforms have been described, [provided by RefSeq, Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
ARHGB_HUMAN, ARHGEF 11, ARHGEF11, DKFZp667F1223, GTRAP 48, GTRAP48, Glutamate transporter EAAT4 associated protein 48, PDZ RhoGEF, Rho guanine exchange factor GEF 11, Rho guanine nucleotide exchange factor 11, Rho guanine nucleotide exchange factor GEF 11, RhoA specic guanine nucleotide exchange factor, RhoGEF glutamate transport modulator, PDZ-RhoGEF |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
PDZ RHOGEF/GTRAP48 |
| Short name: |
PDZ RHOGEF/GTRAP48 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
PDZ RHOGEF/GTRAP48 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
14580 |
| Gene: |
ARHGEF11 |
More about : ARHGEF11 |
| Long gene name: |
Rho guanine nucleotide exchange factor 11 |
| Synonyms gene name: |
Rho guanine nucleotide exchange factor (GEF) 11 |
| Synonyms: |
KIAA0380 GTRAP48 PDZ-RHOGEF |
| Locus: |
1q23, 1 |
| Discovery year: |
2001-02-08 |
| GenBank acession: |
AB002378 |
| Entrez gene record: |
9826 |
| Pubmed identfication: |
10526156 9205841 |
| RefSeq identity: |
NM_198236 |
| Classification: |
Rho guanine nucleotide exchange factors PDZ domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000041292 |