| Long name: |
ALEXA FLUOR 647 Conjugated, BMP2 Polyclonal Antibody |
| Also known as: |
Anti-BMP2 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
BMP2 |
| Specificity: |
This is a highly specific antibody against BMP2 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
265-310/396 |
| Subcellular location: |
Secreted, Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human BMP2 |
| Gene ID Number: |
650 |
| Swiss Prot: |
P12643 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rabbit, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
BMP2 plays an important role in cardiac morphogenesis and is expressed in a variety of tissues including lung, BMPs control fundamental events in early embryonic development, In addition to its osteogenic activity, It is a disulfide-linked homodimer and induces bone and cartilage formation, The functional form of BMP2 is a 26 kDa protein composed of two identical 114 amino acid polypeptide chains linked by a single disulfide bond, brain, liver, organogenesis and adult tissue homeostasis, prostate ovary and small intestine, spleen, BMP2 belongs to the transforming growth factor-beta (TGFB) superfamily of secreted growth factors |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the BMP2 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
BMP2 |
| Short name: |
BMP2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, bone morphogenetic protein 2 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BDA2 and BMP2A, BMP receptor binding, BMP2 and IDBG-52330 and ENSG00000125845 and 650, BMP2 and IDBG-639937 and ENSBTAG00000005111 and 615037, Bmp2 and IDBG-207600 and ENSMUSG00000027358 and 12156, DNA-templated and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0006954 and inflammatory response and biological process this GO :0007219 and Notch signaling pathway and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0007507 and heart development and biological process this GO :0008083 and growth factor activity and molecular function this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009790 and embryo development and biological process this GO :0009887 and organ morphogenesis and biological process this GO :0009986 and cell surface and cellular component this GO :0010628 and positive regulation of gene expression and biological process this GO :0010629 and negative regulation of gene expression and biological process this GO :0010718 and positive regulation of epithelial to mesenchymal transition and biological process this GO :0010862 and positive regulation of pathway-restricted SMAD protein phosphorylation and biological process this GO :0010894 and negative regulation of steroid biosynthetic process and biological process this GO :0010922 and positive regulation of phosphatase activity and biological process this GO :0019211 and phosphatase activator activity and molecular function this GO :0021537 and telencephalon development and biological process this GO :0021978 and telencephalon regionalization and biological process this GO :0030177 and positive regulation of Wnt signaling pathway and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0030282 and bone mineralization and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0030501 and positive regulation of bone mineralization and biological process this GO :0030509 and BMP signaling pathway and biological process this GO :0031648 and protein destabilization and biological process this GO :0032348 and negative regulation of aldosterone biosynthetic process and biological process this GO :0033690 and positive regulation of osteoblast proliferation and biological process this GO :0035051 and cardiac cell differentiation and biological process this GO :0035054 and embryonic heart tube anterior/posterior pattern specification and biological process this GO :0035630 and bone mineralization involved in bone maturation and biological process this GO :0040007 and growth and biological process this GO :0042475 and odontogenesis of dentin-containing tooth and biological process this GO :0042482 and positive regulation of odontogenesis and biological process this GO :0042487 and regulation of odontogenesis of dentin-containing tooth and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0043569 and negative regulation of insulin-like growth factor receptor signaling pathway and biological process this GO :0045165 and cell fate commitment and biological process this GO :0045597 and positive regulation of cell differentiation and biological process this GO :0045600 and positive regulation of fat cell differentiation and biological process this GO :0045666 and positive regulation of neuron differentiation and biological process this GO :0045669 and positive regulation of osteoblast differentiation and biological process this GO :0045778 and positive regulation of ossification and biological process this GO :0045786 and negative regulation of cell cycle and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046332 and SMAD binding and molecular function this GO :0046982 and protein heterodimerization activity and molecular function this GO :0048711 and positive regulation of astrocyte differentiation and biological process this GO :0048762 and mesenchymal cell differentiation and biological process this GO :0048839 and inner ear development and biological process this GO :0051042 and negative regulation of calcium-independent cell-cell adhesion and biological process this GO :0055007 and cardiac muscle cell differentiation and biological process this GO :0055008 and cardiac muscle tissue morphogenesis and biological process this GO :0055114 and oxidation-reduction process and biological process this GO :0060039 and pericardium development and biological process this GO :0060128 and corticotropin hormone secreting cell differentiation and biological process this GO :0060129 and thyroid-stimulating hormone-secreting cell differentiation and biological process this GO :0060317 and cardiac epithelial to mesenchymal transition and biological process this GO :0060389 and pathway-restricted SMAD protein phosphorylation and biological process this GO :0060395 and SMAD protein signal transduction and biological process this GO :0060485 and mesenchyme development and biological process this GO :0060804 and positive regulation of Wnt receptor signaling pathway by BMP signaling pathway and biological process this GO :0061036 and positive regulation of cartilage development and biological process this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0070700 and BMP receptor binding and molecular function this GO :0071363 and cellular response to growth factor stimulus and biological process this GO :0071407 and cellular response to organic cyclic compound and biological process this GO :0071773 and cellular response to BMP stimulus and biological process this GO :0072138 and mesenchymal cell proliferation involved in ureteric bud development and biological process this GO :0090090 and negative regulation of canonical Wnt signaling pathway and biological process this GO :1900745 and positive regulation of p38MAPK cascade and biological process this GO :1901522 and positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus and biological process this GO :2000065 and negative regulation of cortisol biosynthetic process and biological process this GO :2000726 and negative regulation of cardiac muscle cell differentiation and biological process, Extracellular, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000187 and activation of MAPK activity and biological process this GO :0001501 and skeletal system development and biological process this GO :0001649 and osteoblast differentiation and biological process this GO :0001658 and branching involved in ureteric bud morphogenesis and biological process this GO :0001666 and response to hypoxia and biological process this GO :0001701 and in utero embryonic development and biological process this GO :0001837 and epithelial to mesenchymal transition and biological process this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0001938 and positive regulation of endothelial cell proliferation and biological process this GO :0002062 and chondrocyte differentiation and biological process this GO :0003130 and BMP signaling pathway involved in heart induction and biological process this GO :0003181 and atrioventricular valve morphogenesis and biological process this GO :0003203 and endocardial cushion morphogenesis and biological process this GO :0003308 and negative regulation of Wnt receptor signaling pathway involved in heart development and biological process this GO :0004745 and retinol dehydrogenase activity and molecular function this GO :0005102 and receptor binding and molecular function this GO :0005125 and cytokine activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0006029 and proteoglycan metabolic process and biological process this GO :0006355 and regulation of transcription, this GO :0004745 : retinol dehydrogenase activity, this GO :0004745 : retinol dehydrogenase activity and also this GO :0005102 : receptor binding and also this GO :0005125 : cytokine activity and also this GO :0005515 : protein binding and also this GO :0008083 : growth factor activity and also this GO :0019211 : phosphatase activator activity and also this GO :0046332 : SMAD binding and also this GO :0046982 : protein heterodimerization activity and also this GO :0070700 : BMP receptor binding, this GO :0005102 : receptor binding, this GO :0005125 : cytokine activity, this GO :0005515 : protein binding, this GO :0008083 : growth factor activity, this GO :0019211 : phosphatase activator activity, this GO :0046332 : SMAD binding, this GO :0046982 : protein heterodimerization activity, this GO :0070700 : BMP receptor binding, bone morphogenetic protein 2 |
| Identity: |
1069 |
| Gene: |
BMP2 |
More about : BMP2 |
| Long gene name: |
bone morphogenetic protein 2 |
| Synonyms gene: |
BMP2A |
| Locus: |
20p12, 3 |
| Discovery year: |
1990-06-11 |
| Entrez gene record: |
650 |
| Pubmed identfication: |
2376592 |
| Classification: |
Endogenous ligands Bone morphogenetic proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000031833 |