| Long name: |
LAT Primary Polyclonal Antibody |
| Also known as: |
LAT PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
LAT |
| Specificity: |
This is a highly specific antibody against LAT |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human LAT |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
LAT antibody stains thymus and peripheral lymphoid tissues such as T cell areas in lymph nodes and spleen, LAT is expressed in T lymphocytes in interstitial spaces, LAT is not expressed in B cells, epithelial histiocytes and dendritic cells, macrophages, monocytes, plasma cells, platelets and megakaryocytes, which plays an important role in linking engagement of the TCR to the biochemical events of T cell activation, Linker for activation of T cells (LAT) is an integral membrane protein (36 to 38 kD) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
36 kDa phospho tyrosine adapter protein, LAT 1, LAT1, Linker for activation of T cells, Linker for activation of T cells family member 1, p36 38, pp36, Linker for activation of T cell 1 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
LAT |
| Short name: |
LAT Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
linker for activation on T cells (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, Cell surfaces, LAT and IDBG-239499 and ENSG00000213658 and 27040, Lat and IDBG-209436 and ENSMUSG00000030742 and 16797, protein kinase binding, this GO :0001772 and immunological synapse and cellular component this GO :0002260 and lymphocyte homeostasis and biological process this GO :0005070 and SH3/SH2 adaptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0006954 and inflammatory response and biological process this GO :0006955 and immune response and biological process this GO :0007165 and signal transduction and biological process this GO :0007229 and integrin-mediated signaling pathway and biological process this GO :0007265 and Ras protein signal transduction and biological process this GO :0007596 and blood coagulation and biological process this GO :0008180 and COP9 signalosome and cellular component this GO :0009967 and positive regulation of signal transduction and biological process this GO :0010467 and gene expression and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0019722 and calcium-mediated signaling and biological process this GO :0019901 and protein kinase binding and molecular function this GO :0030168 and platelet activation and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0042110 and T cell activation and biological process this GO :0042629 and mast cell granule and cellular component this GO :0043303 and mast cell degranulation and biological process this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0048872 and homeostasis of number of cells and biological process this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0050863 and regulation of T cell activation and biological process, this GO :0005070 : SH3/SH2 adaptor activity, this GO :0005070 : SH3/SH2 adaptor activity and also this GO :0005515 : protein binding and also this GO :0019901 : protein kinase binding, this GO :0005515 : protein binding, this GO :0019901 : protein kinase binding, 26847 and IDBG-638875 and ENSBTAG00000021249 and 514735, linker for activation of T cells |
| Identity: |
18874 |
| Gene: |
LAT |
More about : LAT |
| Long gene name: |
linker for activation of T-cells |
| Synonyms gene name: |
linker for activation of T cells |
| Synonyms: |
LAT1 |
| Synonyms name: |
linker for activation of T cells, transmembrane adaptor |
| Locus: |
16q13 |
| Discovery year: |
2002-07-12 |
| GenBank acession: |
AF036905 |
| Pubmed identfication: |
9489702 |
| Havana BLAST/BLAT: |
OTTHUMG00000131761 |