| Long name: |
Biotin Conjugated, SLC7A5 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SLC7A5 |
| Specificity: |
This is a highly specific antibody against SLC7A5 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
120-140/507 |
| Subcellular location: |
Transmembrane, Helical |
| Source: |
KLH conjugated synthetic peptide derived from human SLC7A5 |
| Gene ID number: |
8140 |
| Swiss Prot: |
Q01650 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Acts as an amino acid exchanger, Acts as the major transporter of tyrosine in fibroblasts, Involved in cellular amino acid uptake, Involved in the cellular activity of small molecular weight nitrosothiols, Involved in the transport of L-DOPA across the blood-brain barrier, Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D, May play an important role in high-grade gliomas, Mediates blood-to-retina L-leucine transport across the inner blood-retinal barrier which in turn may play a key role in maintaining large neutral amino acids as well as neurotransmitters in the neural retina, Plays a role in neuronal cell proliferation (neurogenesis) in brain, and hence plays a role in metal ion homeostasis and toxicity, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta, arginine and tryptophan, high-affinity transport of large neutral amino acids such as phenylalanine, leucine, tyrosine, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane, when associated with SLC3A2/4F2hc, L-homocysteine complexes, Sodium-independent |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
LAT1 E16 D16S469E MPE16 CD98 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SLC7A5 Conjugated |
| Short name: |
Conjugated, SLC7A5 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, SLC7A5 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11063 |
| Gene: |
SLC7A5 |
More about : SLC7A5 |
| Long gene name: |
solute carrier family 7 member 5 |
| Synonyms gene name: |
L system), member 5 , solute carrier family 7 (amino acid transporter light chain |
| Locus: |
16q24, 2 |
| Discovery year: |
1999-01-28 |
| GenBank acession: |
AF077866 |
| Entrez gene record: |
8140 |
| Pubmed identfication: |
9751058 7829099 |
| RefSeq identity: |
NM_003486 |
| Classification: |
Solute carriers CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000137658 |