| Long name: |
FITC Conjugated, IKK Alpha + IKK beta Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
IKK Alpha + IKK beta |
| Specificity: |
This is a highly specific antibody against IKK Alpha + IKK beta |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Secreted |
| Source: |
KLH conjugated synthetic peptide derived from human IKK Alpha/IKK beta |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Additionally, IKK beta, IKK beta activity can also be regulated by MEKK1, IKK beta autophosphorylates which in turn decreases IKK activity and prevents prolonged activation of the inflammatory response, IKK beta has been shown to activate NF-kB and phosphorylate IKB alpha and beta, IKK gamma and IKAP, Once activated, Phosphorylation of 2 sites at the activation loop of IKK beta is essential for activation of IKK by TNF and IL1, Phosphorylation of I-Kappa-B on a serine residue by the IKK complex frees NF-kB from I-Kappa-B and marks it for degradation via ubiquination, IKK Alpha/IKK beta is a member of the IKK complex which is composed of IKK alpha |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
I kappa A kinase 2, I kappa A kinase Alpha, I kappa B kinase 2, I kappa B kinase beta, IKK Î, IKK 1, IKK 2, IKK A, IKK Alpha, IKK Alpha, IKK B, IKK beta, IKKÎ, IKK-Î, IKK1, IKK2, IKKA, IKKA, IKKB, IkBKA, IkBKB, Inhibitor of kappa light chain gene enhancer in B cells, Inhibitor of kappa light polypeptide gene enhancer in B cells, Inhibitor of kappa light polypeptide gene enhancer in B cells kinase beta, Inhibitor of nuclear factor kappa B kinase beta subunit, Inhibitor of nuclear factor kappa B kinase subunit beta, MGC131801, NFKBIKB, Nuclear factor NF kappa B inhibitor kinase beta, Nuclear factor of kappa light chain gene enhancer in B cells inhibitor, ², ², ², IKK-Alpha |
| Description: |
FITC Conjugated is a &alpha, - or alpha protein sometimes glycoprotein present in blood, The IKK Alpha + IKK beta Antibody |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
IKK Alpha + IKK beta Conjugated |
| Short name: |
FITC Conjugated, IKK Alpha + IKK beta Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, IKK a and IKK b (Antibody to) |
| Alternative technique: |
antibodies |