| Long name: |
Biotin Conjugated, Tau protein(Ser552) Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Tau protein Ser552 |
| Specificity: |
This is a highly specific antibody against Tau protein Ser552 |
| Modification: |
Phosphorylation |
| Modification site: |
Ser552 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human Tau protein around the phosphorylation site of Ser552 |
| Gene ID number: |
4137 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome, It expressed in neurons, PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system, Tau proteins subcellular located in the axons of neurons, The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization, and might be involved in the establishment and maintenance of neuronal polarity, in the cytoso l and in association with plasma membrane components, suggesting that tau functions as a linker protein between both, Tau proteins are important Promotes microtubule assembly and stability |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
Disinhibition dementia parkinsonism amyotrophy complex, FTDP 17, FTDP17, G Protein beta 1 gamma 2 subunit interacting factor 1, G protein beta1/gamma2 subunit interacting factor 1, MAPT, MAPTL, MAPTphospho 235, MSTD, MTBT1, MTBT2, Microtubule associated protein tau, Microtubule associated protein tau isoform 4, Mtapt, Neurofibrillary tangle protein, PHF tau, PPND, Paired helical filament tau, RNPTAU, TAU_HUMAN, Tauopathy and respiratory failure, included, pTau, DDPAC, TauSer552 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Tau protein(Ser552) Conjugated |
| Short name: |
Conjugated, Tau protein(Ser552) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, Taurine protein(Ser552) (Antibody to) |
| Alternative technique: |
antibodies |