| Long name: |
ALEXA FLUOR 488 Conjugated, Tau protein(Ser531) Polyclonal Antibody |
| Also known as: |
Anti-Tau protein Ser531 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Tau protein Ser531 |
| Specificity: |
This is a highly specific antibody against Tau protein Ser531 |
| Modification: |
Phosphorylation |
| Modification Site: |
Ser531 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human Tau protein around the phosphorylation site of Ser531 |
| Gene ID Number: |
4137 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome, It expressed in neurons, PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system, Tau proteins subcellular located in the axons of neurons, The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization, and might be involved in the establishment and maintenance of neuronal polarity, in the cytoso l and in association with plasma membrane components, suggesting that tau functions as a linker protein between both, Tau proteins are important Promotes microtubule assembly and stability |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
AI413597, AW045860, DDPAC, Disinhibition dementia parkinsonism amyotrophy complex, FLJ31424, FTDP 17, FTDP17, G Protein beta 1 gamma 2 subunit interacting factor 1, G protein beta1/gamma2 subunit interacting factor 1, MAPT, MAPTL, MGC134287, MGC138549, MGC156663, MSTD, MTBT1, MTBT2, Microtuble-associted protein Tau, Microtubule associated protein tau isoform 4, Mtapt, Neurofibrillary tangle protein, PHF tau, PHF-tau, PPND, Paired helical filament tau, RNPTAU, TAU_HUMAN, Tauopathy and respiratory failure, included, p-Tau protein Ser531, pTau, MAPTphospho S214, TauSer214 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Tau protein(Ser531) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
Tau protein(Ser531) |
| Short name: |
Tau protein(Ser531) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, Taurine protein(Ser531) (Antibody to) |
| Alternative technique: |
antibodies |