| Long name: |
IL-31 Primary Polyclonal Antibody |
| Also known as: |
IL-31 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
IL-31 |
| Specificity: |
This is a highly specific antibody against IL-31 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from mouse IL-31 |
| Gene ID number: |
76399 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Rat, Mouse |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
IL-31, IL-31 activity is mediated through the ligand-induced oligomerization of a dimeric receptor complex containing IL-31 receptor A and oncostatin M receptor, In response to IL-31 binding, RNA levels of IL-31 receptor A and oncostatin M receptor are induced in activated monocytes but are expressed constitutively in epithelial cells, alopecia and skin lesions, and in humans may result in atopic dermatitis, results in the development of pruritis, suggesting that IL-31 may represent a novel target for antipruritic drug development, these proteins activate the JAK/STAT and the AKT signaling pathways, when overexpressed in transgenic mice, Interleukin-31 (IL-31) is a recently discovered T-cell cytokine closely related to IL-6 type cytokines and is preferentially produced by T helper type 2 cells |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
1700013B14RIK, IL31, interleukin-31 precursor, Interleukin-31 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
IL-31 |
| Short name: |
IL-31 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Interleukin-31 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
19372 |
| Gene: |
IL31 |
More about : IL31 |
| Long gene name: |
interleukin 31 |
| Synonyms: |
IL-31 |
| Locus: |
12q24, 31 |
| Discovery year: |
2003-11-06 |
| GenBank acession: |
AY499343 |
| Entrez gene record: |
386653 |
| Pubmed identfication: |
15184896 |
| RefSeq identity: |
NM_001014336 |
| Classification: |
Interleukins |
| Havana BLAST/BLAT: |
OTTHUMG00000168916 |