| Long name: |
Biotin Conjugated, E cadherin Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
E cadherin |
| Specificity: |
This is a highly specific antibody against E cadherin |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
410-460/882 |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human E-cadherin |
| Gene ID number: |
999 |
| Swiss Prot: |
P12830 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
CDH1 is involved in mechanisms regulating cell-cell adhesions, E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors, Has a potent invasive suppressor role, Has a strong inhibitory effect on APP C99 and C83 production, It is a ligand for integrin alpha-E/beta-7, They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types, mobility and proliferation of epithelial cells, Cadherins are calcium-dependent cell adhesion proteins |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
Arc-1, CAM 12/8, CD324, CDH1, CDHE, Cadherin-1, E-cadherin, ECAD, Epithelial cadherin, LCAM, Uvomorulin, UVO |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
E cadherin Conjugated |
| Short name: |
Conjugated, E cadherin Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, E cadherin (Antibody to) |
| Alternative technique: |
antibodies |