| Long name: |
CTLA4 Primary Polyclonal Antibody |
| Also known as: |
CTLA4 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
CTLA4 |
| Specificity: |
This is a highly specific antibody against CTLA4 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
100-150/223 |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CTLA-4/CD152 |
| Gene ID number: |
1493 |
| Swiss Prot: |
P16410 |
| Tested Applications: |
WB |
| Recommended dilutions: |
WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
CD80 and CD86, The affinity of CTLA4 for its natural B7 family ligands, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28, Inhibitory receptor acting as a major negative regulator of T-cell responses |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CD152, CELIAC3, CTLA-4, CTLA4, Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4, GRD4, GSE, IDDM12, CD |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CTLA4 |
| Short name: |
CTLA4 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
cytotoxic T-lymphocyte-associated protein 4 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CD and CD152 and CELIAC3 and CTLA-4 and GRD4 and GSE and IDDM12, CTLA-4 and IDBG-643375 and ENSBTAG00000013170 and 281732, CTLA4 and IDBG-79215 and ENSG00000163599 and 1493, Cell surfaces, Ctla4 and IDBG-159662 and ENSMUSG00000026011 and 12477, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006955 and immune response and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0030889 and negative regulation of B cell proliferation and biological process this GO :0031295 and T cell costimulation and biological process this GO :0042130 and negative regulation of T cell proliferation and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045334 and clathrin-coated endocytic vesicle and cellular component this GO :0045590 and negative regulation of regulatory T cell differentiation and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0050777 and negative regulation of immune response and biological process this GO :0050853 and B cell receptor signaling pathway and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding, cytotoxic T-lymphocyte-associated protein 4 |
| Identity: |
2505 |
| Gene: |
CTLA4 |
More about : CTLA4 |
| Long gene name: |
cytotoxic T-lymphocyte associated protein 4 |
| Synonyms gene: |
CELIAC3 IDDM12 |
| Synonyms gene name: |
celiac disease 3 insulin-dependent diabetes mellitus 12 |
| Synonyms: |
CD152 CD GSE |
| Locus: |
2q33, 2 |
| Discovery year: |
1989-05-25 |
| Entrez gene record: |
1493 |
| Pubmed identfication: |
3220103 8817351 |
| RefSeq identity: |
NM_005214 |
| Classification: |
CD molecules V-set domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000132877 |