| Long name: |
Eph receptor B2 Primary Polyclonal Antibody |
| Also known as: |
Eph receptor B2 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
EphB2 |
| Specificity: |
This is a highly specific antibody against EphB2 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
565-605/1055 |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Eph receptor B2 |
| Gene ID number: |
2048 |
| Swiss Prot: |
P29323 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Also involved in guidance of contralateral inner ear efferent growth cones at the midline and of retinal ganglion cell axons to the optic disk, Controls other aspects of development including angiogenesis, Forward and reverse signaling through the EFNB2/EPHB2 complex regulate movement and adhesion of cells that tubularize the urethra and septate the cloaca, Functions in axon guidance during development, In addition to axon guidance, Involved in the guidance of commissural axons, May function as a tumor suppressor, The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling, Upon activation by EFNB1, abolishes the ARHGEF15-mediated negative regulation on excitatory synapse formation, also regulates dendritic spines development and maturation and stimulates the formation of excitatory synapses, leading to contact-dependent bidirectional signaling into neighboring cells, palate development and in inner ear development through regulation of endolymph production, that form a major interhemispheric connection between the 2 temporal lobes of the cerebral cortex, Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CAPB, Developmentally-regulated Eph-related tyrosine kinase, EK5, ELK-related tyrosine kinase, EPH tyrosine kinase 3, EPH-like kinase 5, EPHB2, EPHT3, EPTH3, ERK, Ephrin type-B receptor 2, Hek5, PCBC, Renal carcinoma antigen NY-REN-47, Tyro5, Tyrosine-protein kinase TYRO5, Tyrosine-protein kinase receptor EPH-3, DRT |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Description: |
2 or 3 and , However, In this sense, When such chemical-signals couple or bind to a receptor, a change in the electrical-activity of a cell, acetylcholine, am olfactory receptor is a protein-molecule that recognizes and responds to , an acetylcholine-receptor recognizes and responds to its endogenous-ligand, chemokinesor cytokines e, e, sometimes in pharmacology, such as enzymes, the term is also used to include other proteins that are drug-targets, they cause some form of cellular/tissue-response, transporters and ion-channels, The receptors are ligand binding factors of type 1, endogenous-chemical signals, g, g, protein-molecules , that receive chemical-signals from outside a cell |
| Gene target: |
Eph receptor B2 |
| Short name: |
Eph receptor B2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Eph receptor B2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3448 |
| Gene: |
ERK |
More about : ERK |
| Long gene name: |
EPH receptor B2 |
| Synonyms gene: |
DRT EPHT3 |
| Synonyms gene name: |
EphB2 |
| Synonyms: |
Hek5 Tyro5 EPHB2 |
| Locus: |
1p36, 12 |
| Discovery year: |
1995-05-09 |
| GenBank acession: |
AF025304 |
| Entrez gene record: |
2048 |
| Pubmed identfication: |
1648701 |
| RefSeq identity: |
NM_017449 |
| Classification: |
Sterile alpha motif domain containing Fibronectin type III domain containing EPH receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000002881 |
| Locus Specific Databases: |
LRG_780 |