| Long name: |
Transferrin receptor Primary Polyclonal Antibody |
| Also known as: |
Transferrin receptor PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Transferrin receptor |
| Specificity: |
This is a highly specific antibody against Transferrin receptor |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
620-670/760 |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Transferrin receptor |
| Gene ID number: |
7037 |
| Swiss Prot: |
P02786 |
| Tested Applications: |
FCM, IF(ICC), IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
FCM(1:20-100), IF(ICC)(1:50-200), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
A second ligand, Endosomal acidification leads to iron release, The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor, Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity), competes for binding with transferrin for an overlapping C-terminal binding site, the heditary hemochromatosis protein HFE, Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CD71, TFR, TFR1, TFRC, TR, TRFR, Transferrin receptor protein 1, p90, T9 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Description: |
2 or 3 and , However, In this sense, When such chemical-signals couple or bind to a receptor, a change in the electrical-activity of a cell, acetylcholine, am olfactory receptor is a protein-molecule that recognizes and responds to , an acetylcholine-receptor recognizes and responds to its endogenous-ligand, chemokinesor cytokines e, e, sometimes in pharmacology, such as enzymes, the term is also used to include other proteins that are drug-targets, they cause some form of cellular/tissue-response, transporters and ion-channels, The receptors are ligand binding factors of type 1, endogenous-chemical signals, g, g, protein-molecules , that receive chemical-signals from outside a cell |
| Gene target: |
Transferrin receptor |
| Short name: |
Transferrin receptor Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Transferrin receptor (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11763 |
| Gene: |
TFRC |
More about : TFRC |
| Long gene name: |
transferrin receptor |
| Synonyms gene name: |
CD71) , transferrin receptor (p90 |
| Synonyms: |
CD71 TFR1 p90 |
| Locus: |
3q29 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
X01060 |
| Entrez gene record: |
7037 |
| Classification: |
CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000155714 |