| Long name: |
ALEXA FLUOR 594 Conjugated, HP1(Tyr43) Polyclonal Antibody |
| Also known as: |
Anti-HP1 Tyr43 PAb ALEXA FLUOR 594 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
HP1 Tyr43 |
| Specificity: |
This is a highly specific antibody against HP1 Tyr43 |
| Modification: |
Phosphorylation |
| Modification Site: |
Tyr43 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from Drosophila Melanogaster HP1 around the phosphorylation site of Tyr43 |
| Gene ID Number: |
34119 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Other Species |
| Cross-reactive species details: |
Fruit Fly |
| Background of the antigen: |
Both domains of HP1 are required for binding to native chromatin in vivo, HP1 alpha may interact with lamin B receptor (LBR), HP1 proteins are relatively small proteins (~25 kDa) with a conserved amino-terminal chromo domain and a structurally related carboxy-terminal motif, It recognizes and binds histone H3 tails methylated at Lys-9, This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane, but they contribute differentially to binding in euchromatin and heterochromatin, leading to epigenetic repression, the chromo shadow domain, HP1 alpha is a component of heterochromatin |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
HP1Hs-alpha HP1 HP1-ALPHA |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated: |
Alexa conjugate 1 |
| Gene target: |
HP1(Tyr43) |
| Short name: |
HP1(Tyr43) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 594 |
| Alternative name: |
ALEXA FLUOR 594, HP1(Tyr43) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1555 |
| Gene: |
CBX5 |
More about : CBX5 |
| Long gene name: |
chromobox 5 |
| Synonyms gene name: |
Drosophila) chromobox homolog 5 , chromobox homolog 5 (Drosophila HP1 alpha) chromobox homolog 5 (HP1 alpha homolog |
| Synonyms name: |
HP1 alpha homolog (Drosophila) |
| Locus: |
12q13, 13 |
| Discovery year: |
1999-10-12 |
| GenBank acession: |
U26311 |
| Entrez gene record: |
23468 |
| Pubmed identfication: |
8663349 |
| RefSeq identity: |
NM_012117 |
| Classification: |
Chromobox family |
| Havana BLAST/BLAT: |
OTTHUMG00000169700 |