| Long name: |
HSP90 alpha Primary Polyclonal Antibody |
| Also known as: |
HSP90 alpha PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
HSP90 alpha |
| Specificity: |
This is a highly specific antibody against HSP90 alpha |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HSP90 Alpha |
| Gene ID number: |
3320 |
| Tested Applications: |
IF(IHC-P), IHC-P |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
However, Hsp90 is a necessary component of fundamental cellular processes such as hormone signaling and cell cycle control, Hsp90 is part of the cells powerful network of chaperones to fight the deleterious consequences of protein unfolding caused by nonphysiological conditions, Hsp90a and Hsp90b which are encoded by separate genes, In this context several key regulatory proteins such as steriod receptors, It has been suggested that Hsp90 acts as a capacitor for morphological evolution by buffering widespread variation, These ubiquitous and highly conserved proteins account for 1-2% of all cellular proteins in most cells, cell cycle kinases involved in signal transduction and p53 have been identified as substrates of Hsp90, in the absence of stress, which may affect morphogenic pathways, In mammalian cells there are at least two Hsp90 isoforms |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
D6S182, FLJ26984, FLJ31884, HS90A_HUMAN, HSP 84, HSP 86, HSP84, HSP86, HSP89A, HSP90 Beta, HSP90A, HSP90AA1, HSP90AB1, HSP90ALPHA, HSP90B, HSP90N, HSPC1, HSPC2, HSPCA, HSPCAL1, HSPCAL3, HSPCAL4, HSPCB, HSPN, HSPN, Heat shock 86 kDa, Heat shock protein 90kDa alpha cytosolic class A member 1, Heat shock protein 90kDa alpha cytosolic class B member 1, Heat shock protein HSP 90 alpha, Heat shock protein HSP 90 beta, Heat shock protein HSP 90-alpha, Hsp 90, Hsp89, Hsp90, LAP2, LPS associated protein 2, Lipopolysaccharide associated protein2, NY REN 38 antigen, Renal carcinoma antigen NY REN 38, Renal carcinoma antigen NY-REN-38, class A member 2, heat shock 90kDa protein 1 alpha, heat shock protein 90kDa alpha cytosolic, HSP90 alpha Thr5/7 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
HSP90 alpha |
| Short name: |
HSP90 alpha Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
HSP90 a (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
5253 |
| Gene: |
HSP90AA1 |
More about : HSP90AA1 |
| Long gene name: |
heat shock protein 90 alpha family class A member 1 |
| Synonyms gene: |
HSPC1 HSPCA |
| Synonyms gene name: |
alpha heat shock 90kDa protein 1, alpha heat shock protein 90kDa alpha (cytosolic), class A member 1 , heat shock 90kD protein 1 |
| Synonyms: |
Hsp89 Hsp90 FLJ31884 HSP90N |
| Locus: |
14q32, 31 |
| Discovery year: |
1990-06-27 |
| GenBank acession: |
M27024 |
| Entrez gene record: |
3320 |
| Pubmed identfication: |
2527334 16269234 |
| RefSeq identity: |
NM_005348 |
| Classification: |
Heat shock 90kDa proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000171752 |