| Long name: |
ALEXA FLUOR 488 Conjugated, VE Cadherin Polyclonal Antibody |
| Also known as: |
Anti-VE Cadherin PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
VE Cadherin |
| Specificity: |
This is a highly specific antibody against VE Cadherin |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
621-660/784 |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from mouse Vascular endolial cell cadherin |
| Gene ID Number: |
12562 |
| Swiss Prot: |
P55284 |
| Tested applications: |
IF(ICC), IF(IHC-P), FCM |
| Recommended dilutions: |
IF(ICC)(1:50-200), IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascular lumen, PARD3, Required for activation of PRKCZ and for localization of phosphorylated PRKCZ, TIAM1 and RAP1B to the cell junction, These effects are mediated by recruitment and activation of the Par polarity complex and RAP1B, They preferentially interact with themselves in a homophilic manner in connecting cells, This cadherin may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions, cadherins may thus contribute to the sorting of heterogeneous cell types, Cadherins are calcium-dependent cell adhesion proteins |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
AA48225, Cadherin-5, Cd144, Cdh5, VE-Cad, VE-cadherin, VECD, VEcad, Vascular endothelial cadherin, Vec, 7B4 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the VE Cadherin Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
VE Cadherin |
| Short name: |
VE Cadherin Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, VE Cadherin (Antibody to) |
| Alternative technique: |
antibodies |