| Long name: |
TARDBP Primary Polyclonal Antibody |
| Also known as: |
TARDBP PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
TARDBP |
| Specificity: |
This is a highly specific antibody against TARDBP |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
120-170/414 |
| Subcellular location: |
Nucleus |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TDP-43 |
| Gene ID number: |
23435 |
| Swiss Prot: |
Q13148 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Can repress HIV-1 transcription by binding to the HIV-1 long terminal repeat, Involved in the regulation of CFTR splicing, It promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon, May also be involved in microRNA biogenesis, Stabilizes the low molecular weight neurofilament (NFL) mRNA through a direct interaction with the 3' UTR, The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis, apoptosis and cell division, DNA and RNA-binding protein which regulates transcription and splicing |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
TAR DNA-binding protein 43, TARDBP, TDP-43, TDP43, ALS10 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
TARDBP |
| Short name: |
TARDBP Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
TARDBP (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11571 |
| Gene: |
TARDBP |
More about : TARDBP |
| Long gene name: |
TAR DNA binding protein |
| Synonyms: |
TDP-43 ALS10 |
| Locus: |
1p36, 22 |
| Discovery year: |
2000-01-28 |
| GenBank acession: |
U23731 |
| Entrez gene record: |
23435 |
| Pubmed identfication: |
7745706 |
| RefSeq identity: |
NM_007375 |
| Classification: |
RNA binding motif containing |
| Havana BLAST/BLAT: |
OTTHUMG00000002120 |
| Locus Specific Databases: |
ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database LRG_659 |