| Long name: |
Fibulin 1 Primary Polyclonal Antibody |
| Also known as: |
Fibulin 1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Fibulin 1 |
| Specificity: |
This is a highly specific antibody against Fibulin 1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Fibulin 1 |
| Gene ID number: |
2192 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
By contrast, Cells transfected to overproduce fibulin-1 displayed reduced velocity, Fibulin-1 was also found to inhibit the motility of a variety of cell types on FN substrata, Fibulin-1 was found to have pronounced inhibitory effects on the cell attachment and spreading promoted by FN, For example, Similarly, distance of movement and persistence time on FN substrata, epidermal carcinoma (A431), incorporation of fibulin-1 into collagen gels lacking FN had no effect on the migration of endocardial cushion cells, melanoma (A375 SM), rat pulmonary aortic smooth muscle cells (PAC1) and Chinese hamster ovary (CHO) cells was inhibited by the presence of fibulin-1 bound to FN-coated Boyden chamber membranes, the FN-dependent haptotactic motility of breast carcinoma (MDA MB231) cells, the incorporation of fibulin-1 into FN-containing type I collagen gels inhibited the invasion of endocardial cushion mesenchymal cells migrating from cultured embryonic heart explants, Fibulin-1 is an extracellular matrix protein often associated with fibronectin (FN) in vivo |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
BM 90, FBLN, FBLN1, FIBL 1, FIBL1, Fibulin 1, Basement membrane protein 90 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Fibulin 1 |
| Short name: |
Fibulin 1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Fibulin 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3600 |
| Gene: |
FBLN1 |
More about : FBLN1 |
| Long gene name: |
fibulin 1 |
| Synonyms: |
FBLN |
| Locus: |
22q13, 31 |
| Discovery year: |
1994-02-08 |
| Entrez gene record: |
2192 |
| Pubmed identfication: |
2269669 1400330 |
| RefSeq identity: |
NM_006486 |
| Classification: |
Fibulins |
| Havana BLAST/BLAT: |
OTTHUMG00000151340 |