| Long name: |
Cyclooxygenase 2 Primary Polyclonal Antibody |
| Also known as: |
Cyclooxygenase 2 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Cyclooxygenase 2 |
| Specificity: |
This is a highly specific antibody against Cyclooxygenase 2 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
560-600/604 |
| Subcellular location: |
Intracellular |
| Source: |
KLH conjugated synthetic peptide derived from mouse Cyclooxygenase 2 |
| Gene ID number: |
19225 |
| Swiss Prot: |
Q05769 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Constitutively expressed in some tissues in physiological conditions, In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), PTGS2 is responsible for production of inflammatory prostaglandins, Up-regulation of PTGS2 is also associated with increased cell adhesion, a committed step in prostanoid synthesis, and in pathological conditions, kidney and brain, phenotypic changes, proliferation and resistance to apoptosis, resistance to apoptosis and tumor angiogenesis, such as in cancer, such as the endothelium, which plays important roles in modulating motility, Converts arachidonate to prostaglandin H2 (PGH2) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Cox-2, Cyclooxygenase-2, Glucocorticoid-regulated inflammatory cyclooxygenase, Gripghs, Macrophage activation-associated marker protein P71/73, PES-2, PGH synthase 2, PGHS-2, PHS II, PHS-2, Pghs-b, Pghs2, Prostaglandin G/H synthase 2, Prostaglandin H2 synthase 2, Prostaglandin-endoperoxide synthase 2, Ptgs2, TIS1, TIS1 protein, COX2 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Cyclooxygenase 2 |
| Short name: |
Cyclooxygenase 2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Cyclooxygenase 2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9605 |
| Gene: |
PTGS2 |
More about : PTGS2 |
| Long gene name: |
prostaglandin-endoperoxide synthase 2 |
| Synonyms gene name: |
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| Synonyms: |
COX2 |
| Synonyms name: |
prostaglandin G/H synthase 2 cyclooxygenase 2 |
| Locus: |
1q31, 1 |
| Discovery year: |
1992-10-28 |
| GenBank acession: |
D28235 |
| Entrez gene record: |
5743 |
| Pubmed identfication: |
1380156 |
| RefSeq identity: |
NM_000963 |
| Havana BLAST/BLAT: |
OTTHUMG00000035473 |