| Long name: |
Biotin Conjugated, Neuropilin-1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Neuropilin 1 |
| Specificity: |
This is a highly specific antibody against Neuropilin 1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
880-923/923 |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from human neuropilin-1 |
| Gene ID number: |
8829 |
| Swiss Prot: |
O14786 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis, It binds to semaphorin 3A, It may also induce apoptosis by sequestering VEGF-165, It may regulate VEGF-induced angiogenesis, It mediates the chemorepulsant activity of semaphorins, Its expression has an averse effect on blood vessel number and integrity, May bind as well various members of the semaphorin family, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B, The soluble isoform 2 binds VEGF-165 and appears to inhibit its binding to cells, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system, The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
BDCA4, CD304, NRP, NRP1, Neuropilin-1, VEGF165R, Vascular endothelial cell growth factor 165 receptor, NP1 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Neuropilin-1 Conjugated |
| Short name: |
Conjugated, Neuropilin-1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, Neuropilin-1 (Antibody to) |
| Alternative technique: |
antibodies |