| Long name: |
ALEXA FLUOR 488 Conjugated, Neuropilin-1 Polyclonal Antibody |
| Also known as: |
Anti-Neuropilin 1 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Neuropilin 1 |
| Specificity: |
This is a highly specific antibody against Neuropilin 1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
880-923/923 |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human neuropilin-1 |
| Gene ID Number: |
8829 |
| Swiss Prot: |
O14786 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis, It binds to semaphorin 3A, It may also induce apoptosis by sequestering VEGF-165, It may regulate VEGF-induced angiogenesis, It mediates the chemorepulsant activity of semaphorins, Its expression has an averse effect on blood vessel number and integrity, May bind as well various members of the semaphorin family, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B, The soluble isoform 2 binds VEGF-165 and appears to inhibit its binding to cells, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system, The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
BDCA4, CD304, NRP, NRP1, Neuropilin-1, VEGF165R, Vascular endothelial cell growth factor 165 receptor, NP1 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Neuropilin-1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
Neuropilin-1 |
| Short name: |
Neuropilin-1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, Neuropilin-1 (Antibody to) |
| Alternative technique: |
antibodies |