Cyclin D1 Antibody, Cy5.5 Conjugated

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Catalog number: bs-0623R-Cy5.5
Price: 350 €
Supplier: Bioss Primary Conjugated Antibodies
Product name: Cyclin D1 Antibody, Cy5.5 Conjugated
Quantity: 0.1ml
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More details :

Long name: Cy5, 5 Conjugated, Cyclin D1 Polyclonal Antibody
Category: Conjugated Primary Antibodies
Conjugation: Cy5, 5, 5, Cy5
Host Organism: Rabbit (Oryctolagus cuniculus)
Target Antigen: Cyclin D1
Specificity: This is a highly specific antibody against Cyclin D1
Modification: Unmodified
Modification site: None
Clonality: Polyclonal
Clone: Polyclonal antibody
Concentration: 1ug per 1ul
Immunogen_range: 70-120/295
Subcellular location: Nucleus, Cytoplasm
Source: KLH conjugated synthetic peptide derived from mouse Cyclin D1
Gene ID number: 12443
Swiss Prot: P25322
Tested applications: IF(ICC), IF(IHC-P), FCM
Recommended dilutions: IF(ICC)(1:50-200), IF(IHC-P)(1:50-200), FCM(1:20-100)
Crossreactivity: Goat, Mouse, Rat, Human
Crossreactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background: Also substrate for SMAD3, Component of the ternary complex, Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals, Exhibits transcriptional corepressor activity with INSM1 on the NEUROD1 and INS promoters in a cell cycle-independent manner (By similarity), Hypophosphorylates RB1 in early G(1) phase, Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase, cyclin D1/CDK4/CDKN1B, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity, required for nuclear translocation and activity of the cyclin D-CDK4 complex, Regulatory component of the cyclin D1-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition
Purification method: This antibody was purified via Protein A
Storage conditions: 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission: 675nm/694nm
Synonyms: AI32739, Ccnd1, CycD1, Cyl-1, G1/S-specific cyclin-D1, PRAD1, bcl-1, cD1
Properties: Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Conjugated: These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths
Gene target: Cyclin D1 Conjugated
Short name: Conjugated, Cyclin D1 Antibody
Technique: antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label: 5, Cy5
Alternative name: cyanine 5, 5 coupled, Cyclin D1 (Antibody to)
Alternative technique: antibodies

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