| Long name: |
WWOX Primary Polyclonal Antibody |
| Also known as: |
WWOX PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
WWOX |
| Specificity: |
This is a highly specific antibody against WWOX |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
1-50/414 |
| Subcellular location: |
Mitochondrion, Nucleus, Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human WWOX |
| Gene ID number: |
51741 |
| Swiss Prot: |
Q9NZC7 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Acts as a tumor suppressor and plays a role in apoptosis, Inhibits Wnt signaling, May also play a role in tumor necrosis factor (TNF)-mediated cell death, May function synergistically with p53/TP53 to control genotoxic stress-induced cell death, Plays a role in TGFB1 signaling and TGFB1-mediated cell death, Required for normal bone development (By similarity), probably by sequestering DVL2 in the cytoplasm, Putative oxidoreductase |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
D16S432E, EIEE28, FRA16D, Fragile site FRA16D oxidoreductase, HHCMA56, PRO0128, SCAR12, SDR41C1, Short chain dehydrogenase/reductase family 41C member 1, WOX1, WW domain-containing oxidoreductase, WWOX, FOR |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
WWOX |
| Short name: |
WWOX Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
WW domain containing oxidoreductase (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
WWOX and IDBG-43129 and ENSG00000186153 and 51741, WWOX and IDBG-629302 and ENSBTAG00000015894 and 618792, Wwox and IDBG-194458 and ENSMUSG00000004637 and 80707, coenzyme binding, nuclei, this GO :0001649 and osteoblast differentiation and biological process this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005902 and microvillus and cellular component this GO :0008152 and metabolic process and biological process this GO :0008202 and steroid metabolic process and biological process this GO :0016055 and Wnt signaling pathway and biological process this GO :0016491 and oxidoreductase activity and molecular function this GO :0019899 and enzyme binding and molecular function this GO :0030178 and negative regulation of Wnt signaling pathway and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046983 and protein dimerization activity and molecular function this GO :0048037 and cofactor binding and molecular function this GO :0048705 and skeletal system morphogenesis and biological process this GO :0050662 and coenzyme binding and molecular function this GO :0055114 and oxidation-reduction process and biological process this GO :0071560 and cellular response to transforming growth factor beta stimulus and biological process this GO :0072332 and intrinsic apoptotic signaling pathway by p53 class mediator and biological process this GO :0097191 and extrinsic apoptotic signaling pathway and biological process this GO :2001238 and positive regulation of extrinsic apoptotic signaling pathway and biological process this GO :2001241 and positive regulation of extrinsic apoptotic signaling pathway in absence of ligand and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0016491 : oxidoreductase activity and also this GO :0019899 : enzyme binding and also this GO :0046983 : protein dimerization activity and also this GO :0048037 : cofactor binding and also this GO :0050662 : coenzyme binding, this GO :0016491 : oxidoreductase activity, this GO :0019899 : enzyme binding, this GO :0046983 : protein dimerization activity, this GO :0048037 : cofactor binding, this GO :0050662 : coenzyme binding, WW domain containing oxidoreductase |
| Identity: |
12799 |
| Gene: |
WWOX |
More about : WWOX |
| Long gene name: |
WW domain containing oxidoreductase |
| Synonyms gene name: |
WW domain-containing oxidoreductase |
| Synonyms: |
FOR WOX1 SDR41C1 |
| Synonyms name: |
member 1 , short chain dehydrogenase/reductase family 41C |
| Locus: |
16q23, 1-q23, 2 |
| Discovery year: |
2000-07-31 |
| GenBank acession: |
AF187015 |
| Entrez gene record: |
51741 |
| Pubmed identfication: |
10786676 10861292 19027726 |
| Classification: |
Short chain dehydrogenase/reductase superfamily |
| Havana BLAST/BLAT: |
OTTHUMG00000176851 |