| Long name: |
FITC Conjugated, IL2RA Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
IL2RA |
| Specificity: |
This is a highly specific antibody against IL2RA |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
258-268/268 |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from mouse CD25/IL2RA |
| Gene ID number: |
16184 |
| Swiss Prot: |
P01590 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Alternately-spliced IL2RA mRNAs have been isolated, Homodimeric alpha chains (IL2RA) result in low-affinity receptor, Mutations in this gene are associated with interleukin 2 receptor alpha deficiency, Normally an integral-membrane protein, Nov 2009], but the significance of each is presently unknown, constitute the high-affinity IL2 receptor, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis, together with the common gamma chain (IL2RG), while homodimeric beta (IL2RB) chains produce a medium-affinity receptor, The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, [provided by RefSeq |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
CD25 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
IL2RA Conjugated |
| Short name: |
FITC Conjugated, IL2RA Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
alpha (Antibody to), fluorecein coupled, interleukin 2 receptor |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CD25 and IDDM10 and IL2R and p55 and TCGFR, Cell surfaces, IL2RA and IDBG-50566 and ENSG00000134460 and 3559, IL2RA and IDBG-637067 and ENSBTAG00000020892 and 281861, Il2ra and IDBG-136654 and ENSMUSG00000026770 and 16184, alpha, interleukin-2 binding, this GO :0002437 and inflammatory response to antigenic stimulus and biological process this GO :0004911 and interleukin-2 receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006915 and apoptotic process and biological process this GO :0006924 and activation-induced cell death of T cells and biological process this GO :0006955 and immune response and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007219 and Notch signaling pathway and biological process this GO :0008144 and drug binding and molecular function this GO :0008283 and cell proliferation and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0019976 and interleukin-2 binding and molecular function this GO :0042102 and positive regulation of T cell proliferation and biological process this GO :0042104 and positive regulation of activated T cell proliferation and biological process this GO :0042130 and negative regulation of T cell proliferation and biological process this GO :0043029 and T cell homeostasis and biological process this GO :0045582 and positive regulation of T cell differentiation and biological process this GO :0046013 and regulation of T cell homeostatic proliferation and biological process this GO :0050672 and negative regulation of lymphocyte proliferation and biological process this GO :0050687 and negative regulation of defense response to virus and biological process this GO :0050728 and negative regulation of inflammatory response and biological process this GO :0050777 and negative regulation of immune response and biological process, this GO :0004911 : interleukin-2 receptor activity, this GO :0004911 : interleukin-2 receptor activity and also this GO :0005515 : protein binding and also this GO :0008144 : drug binding and also this GO :0019976 : interleukin-2 binding, this GO :0005515 : protein binding, this GO :0008144 : drug binding, this GO :0019976 : interleukin-2 binding, interleukin 2 receptor |
| Identity: |
6008 |
| Gene: |
IL2RA |
More about : IL2RA |
| Long gene name: |
interleukin 2 receptor subunit alpha |
| Synonyms gene: |
IL2R IDDM10 |
| Synonyms gene name: |
alpha , insulin-dependent diabetes mellitus 10 interleukin 2 receptor |
| Locus: |
10p15, 1 |
| Discovery year: |
1990-01-22 |
| GenBank acession: |
X01057 |
| Entrez gene record: |
3559 |
| Pubmed identfication: |
3925551 17676041 |
| RefSeq identity: |
NM_000417 |
| Classification: |
Sushi domain containing CD molecules Interleukin receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000017616 |
| Locus Specific Databases: |
IL2RAbase: Mutation registry for Interleuken 2 receptor &, deficiency LRG_73 , #945 |