| Long name: |
IL2RA Primary Polyclonal Antibody |
| Also known as: |
IL2RA PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
IL2RA |
| Specificity: |
This is a highly specific antibody against IL2RA |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
258-268/268 |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from mouse CD25/IL2RA |
| Gene ID number: |
16184 |
| Swiss Prot: |
P01590 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Alternately-spliced IL2RA mRNAs have been isolated, Homodimeric alpha chains (IL2RA) result in low-affinity receptor, Mutations in this gene are associated with interleukin 2 receptor alpha deficiency, Normally an integral-membrane protein, Nov 2009], but the significance of each is presently unknown, constitute the high-affinity IL2 receptor, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis, together with the common gamma chain (IL2RG), while homodimeric beta (IL2RB) chains produce a medium-affinity receptor, The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, [provided by RefSeq |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
IL-2 receptor subunit alpha, IL-2-RA, IL-2R subunit alpha, IL2-RA, Il2r, Il2ra, Interleukin-2 receptor subunit alpha, Ly-43, p55, CD25 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
IL2RA |
| Short name: |
IL2RA Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
alpha (Antibody to), interleukin 2 receptor |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CD25 and IDDM10 and IL2R and p55 and TCGFR, Cell surfaces, IL2RA and IDBG-50566 and ENSG00000134460 and 3559, IL2RA and IDBG-637067 and ENSBTAG00000020892 and 281861, Il2ra and IDBG-136654 and ENSMUSG00000026770 and 16184, alpha, interleukin-2 binding, this GO :0002437 and inflammatory response to antigenic stimulus and biological process this GO :0004911 and interleukin-2 receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006915 and apoptotic process and biological process this GO :0006924 and activation-induced cell death of T cells and biological process this GO :0006955 and immune response and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007219 and Notch signaling pathway and biological process this GO :0008144 and drug binding and molecular function this GO :0008283 and cell proliferation and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0019976 and interleukin-2 binding and molecular function this GO :0042102 and positive regulation of T cell proliferation and biological process this GO :0042104 and positive regulation of activated T cell proliferation and biological process this GO :0042130 and negative regulation of T cell proliferation and biological process this GO :0043029 and T cell homeostasis and biological process this GO :0045582 and positive regulation of T cell differentiation and biological process this GO :0046013 and regulation of T cell homeostatic proliferation and biological process this GO :0050672 and negative regulation of lymphocyte proliferation and biological process this GO :0050687 and negative regulation of defense response to virus and biological process this GO :0050728 and negative regulation of inflammatory response and biological process this GO :0050777 and negative regulation of immune response and biological process, this GO :0004911 : interleukin-2 receptor activity, this GO :0004911 : interleukin-2 receptor activity and also this GO :0005515 : protein binding and also this GO :0008144 : drug binding and also this GO :0019976 : interleukin-2 binding, this GO :0005515 : protein binding, this GO :0008144 : drug binding, this GO :0019976 : interleukin-2 binding, interleukin 2 receptor |
| Identity: |
6008 |
| Gene: |
IL2RA |
More about : IL2RA |
| Long gene name: |
interleukin 2 receptor subunit alpha |
| Synonyms gene: |
IL2R IDDM10 |
| Synonyms gene name: |
alpha , insulin-dependent diabetes mellitus 10 interleukin 2 receptor |
| Synonyms: |
CD25 |
| Locus: |
10p15, 1 |
| Discovery year: |
1990-01-22 |
| GenBank acession: |
X01057 |
| Entrez gene record: |
3559 |
| Pubmed identfication: |
3925551 17676041 |
| RefSeq identity: |
NM_000417 |
| Classification: |
Sushi domain containing CD molecules Interleukin receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000017616 |
| Locus Specific Databases: |
IL2RAbase: Mutation registry for Interleuken 2 receptor &, deficiency LRG_73 , #945 |