| Long name: |
Integrin beta 1 Primary Polyclonal Antibody |
| Also known as: |
Integrin beta 1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Integrin beta 1 |
| Specificity: |
This is a highly specific antibody against Integrin beta 1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
10-60/798 |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Integrin beta 1 |
| Gene ID number: |
3688 |
| Swiss Prot: |
P05556 |
| Tested Applications: |
IF(ICC), IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(ICC)(1:50-200), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration, Alpha-4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin, Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands, In case of HIV-1 infection, Integrin alpha-1/beta-1, Integrin alpha-3/beta-1 is a receptor for epiligrin, Integrin alpha-4/beta-1 is a receptor for VCAM1, Integrin alpha-5/beta-1 is a receptor for fibrinogen, Integrin alpha-9/beta-1 is a receptor for VCAM1, Integrin alpha-V/beta-1 is a receptor for vitronectin, Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G-E-R in collagen, Integrins alpha-2/beta-1, Isoform beta-1B interferes with isoform beta-1A resulting in a dominant negative effect on cell adhesion and migration (in vitro), It recognizes the sequence A-E-I-D-G-I-E-L in cytotactin, It recognizes the sequence Q-I-D-S in VCAM1, alpha-10/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen, alpha-11/beta-1 and alpha-V/beta-1 are receptors for fibronectin, alpha-2/beta-1, alpha-2/beta-1, alpha-3/beta-1, alpha-4/beta-1, alpha-5/beta-1, alpha-6/beta-1 and alpha-7/beta-1 are receptors for lamimin, alpha-8/beta-1, cytotactin and osteopontin, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions, thrombospondin and CSPG4, Integrins alpha-1/beta-1 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
FNRB, Fibronectin receptor subunit beta, GPIIA, Glycoprotein IIa, ITGB1, Integrin beta-1, MDF2, MSK12, VLA-4 subunit beta, VLA-BETA, VLAB, CD29 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Integrin beta 1 |
| Short name: |
Integrin beta 1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Integrin b 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3781 |
| Gene: |
ITGB1P1 |
More about : ITGB1P1 |
| Long gene name: |
integrin subunit beta 1 pseudogene 1 |
| Synonyms gene: |
FNRBL |
| Synonyms gene name: |
beta polypeptide-like integrin beta 1 pseudogene 1 , fibronectin receptor |
| Synonyms: |
ITGB1L |
| Locus: |
19p13, 12 |
| Discovery year: |
1989-05-19 |
| Entrez gene record: |
100422691 |
| Pubmed identfication: |
1979054 |
| RefSeq identity: |
NG_024150 |
| Havana BLAST/BLAT: |
OTTHUMG00000183370 |