| Long name: |
MMP-1 Primary Polyclonal Antibody |
| Also known as: |
MMP-1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
MMP-1 |
| Specificity: |
This is a highly specific antibody against MMP-1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
430-464/464 |
| Subcellular location: |
Secreted |
| Source: |
KLH conjugated synthetic peptide derived from rat MMP1 |
| Gene ID number: |
300339 |
| Tested Applications: |
IF(IHC-P), IHC-P |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity: |
Rat, Mouse |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
All MMPs are synthesized as proenzymes, Alzheimer's, Collectively, In addition, In general, MMPs are considered to play an important role in wound healing, Thus, a hinge region, a propeptide, a signal peptide, and a C terminal hemopexin like domain allow categorization of MMPs into the collagenase, and a catalytic domain containing the highly conserved zinc binding site characterizes the structure of the MMPs, and in cancer cell invasion and metastasis, and in diseases such as multiple sclerosis, and most of them are secreted from the cells as proenzymes, angiogenesis and tissue remodeling, apoptosis, arthritis, atherosclerosis, bone elongation, embryo development, fibronectin, fibronectin like repeats, gelatinase, glumerulonephritis, including fibrillar and non fibrillar collagens, laminin and basement membrane glycoproteins, lupus, malignant gliomas, periodontis, stomelysin and membrane type MMP subfamilies, the activation of these proenzymes is a critical step that leads to extracellular matrix breakdown, these enzymes can degrade all the components of the extracellular matrix, tissue ulceration, uterine involution, The matrix metalloproteinases (MMPs) are a family of at least eighteen secreted and membrane bound zincendopeptidases |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
27 kDa interstitial collagenase, CLG, Fibroblast collagenase, Interstitial collagenase, MMP 1, MMP-1, MMP1, MMP1_HUMAN, Matrix Metalloproteinase 1, Matrix metallopeptidase 1 interstitial collagenase, Matrix metalloprotease 1, Matrix metalloproteinase-1, OTTHUMP00000045866, collagenase, fibroblast, CLGN |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
MMP-1 |
| Short name: |
MMP-1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
MMP-1 (Antibody to) |
| Alternative technique: |
antibodies |