| Long name: |
NIS Primary Polyclonal Antibody |
| Also known as: |
NIS PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
NIS |
| Specificity: |
This is a highly specific antibody against NIS |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
542-592/618 |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from mouse NIS |
| Swiss Prot: |
Q99PN0 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
It is a membrane bound glycoprotein with 13 membrane spanning domains and 14 extramembranous domains, It may represent an autoantigen in thyroid, Human Sodium Iodide Symporter (hNIS) is responsible for iodide concentrating ability within thyroid follicular cells, catalyzes Na+/I- symporter activity plays a role in iodide transport and thyroid hormone generation |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
NIS, Na+/I- cotransporter, Na+/I- cotransporter, Na+/I- symporter, Na+/I- symporter, Na+/I-symporter, SC5A5_HUMAN, SLC5A5, Sodium-iodide symporter, Sodium/iodide cotransporter, Solute carrier family 5, Solute carrier family 5 member 5, Solute carrier family 5 sodium iodide symporter member 5, sodium iodide symporter, Na+/I- cotransporter |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
NIS |
| Short name: |
NIS Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
NIS (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11040 |
| Gene: |
SLC5A5 |
More about : SLC5A5 |
| Long gene name: |
solute carrier family 5 member 5 |
| Synonyms gene name: |
member 5 , member 5 solute carrier family 5 (sodium/iodide cotransporter), solute carrier family 5 (sodium iodide symporter) |
| Synonyms: |
NIS |
| Locus: |
19p13, 11 |
| Discovery year: |
1997-04-16 |
| Entrez gene record: |
6528 |
| Pubmed identfication: |
9231811 |
| Classification: |
Solute carriers |
| Havana BLAST/BLAT: |
OTTHUMG00000183447 |