| Long name: |
Biotin Conjugated, MMP-7 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
MMP-7 |
| Specificity: |
This is a highly specific antibody against MMP-7 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
165-210/264 |
| Subcellular location: |
Secreted |
| Source: |
KLH conjugated synthetic peptide derived from mouse MMP7 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
It lacks the hemopexin-like domain common to other members of the MMPs, MMP-7 can activate pro-MMP-1 and pro-MMP-9 but not pro-MMP-2, MMP-7 is closely related to the stromelysin family members but is encoded by a different gene, MMP-7 is secreted as a 28kD proenzyme and can be activated in vitro by organomercurials and trypsin and in vivo by MMP-3 to a 18kD active MMP-7 enzyme, MMP-7 is the smallest of all the MMPs consisting of a pro-peptide domain and a catalytic domain, MMP-7 is widely expressed having been reported in elevated levels in cycling endometrium as well as in colorectal cancers and adenomas, Once activated, and approximately 50% of gliomas, elastin, fibronectin, gelatin, hepatocellular carcinomas, laminin and proteoglycans, rectal carcinomas, 23) cleaves a number of substrates including collagen types IV and X, 4, 24, Matrix metalloproteinase-7 (MMP-7) also known as matrilysin and PUMP (EC 3 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
MMP 7, MMP7, MPSL1, Matrilysin uterine, Matrin, Matrix Metalloproteinase 7, PUMP 1, PUMP1, Pump 1 protease, Uterine Matrilysin, Uterine metalloproteinase, Matrilysin |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
MMP-7 Conjugated |
| Short name: |
Conjugated, MMP-7 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, MMP-7 (Antibody to) |
| Alternative technique: |
antibodies |