| Long name: |
MMP2 Primary Polyclonal Antibody |
| Also known as: |
MMP2 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
MMP2 |
| Specificity: |
This is a highly specific antibody against MMP2 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
20-70/476 |
| Subcellular location: |
Secreted |
| Source: |
MAT conjugated synthetic peptide derived from human MMP2 |
| Gene ID number: |
4313 |
| Swiss Prot: |
P08253 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Also cleaves KISS at a Gly-|-Leu bond, Appears to have a role in myocardial cell death pathways, As well as degrading extracellular matrix proteins, Cleaves GSK3beta in vitro, Contributes to myocardial oxidative stress by regulating the activity of GSK3beta, Involved in the formation of the fibrovascular tissues in association with MMP14, Isoform 2: Mediates the proteolysis of CHUK/IKKA and initiates a primary innate immune response by inducing mitochondrial-nuclear stress signaling with activation of the pro-inflammatory NF-kappaB, Ligand for integrinv/beta3 on the surface of blood vessels, NFAT and IRF transcriptional pathways, PEX, and atherosclerotic plaque rupture, angiogenesis, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction, inflammation, posseses anti-angiogenic and anti-tumor properties and inhibits cell migration and cell adhesion to FGF2 and vitronectin, the C-terminal non-catalytic fragment of MMP2, tissue repair, tumor invasion, Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
72 kDa gelatinase, 72 kDa type IV collagenase, CLG4A, Gelatinase A, MMP-2, MMP-II, MMP2, MONA, Matrix metalloproteinase-2, TBE-1, CLG4 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
MMP2 |
| Short name: |
MMP2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
MMP2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
7166 |
| Gene: |
MMP2 |
More about : MMP2 |
| Long gene name: |
matrix metallopeptidase 2 |
| Synonyms gene: |
CLG4 CLG4A |
| Synonyms gene name: |
72kDa gelatinase, 72kDa type IV collagenase) , matrix metalloproteinase 2 (gelatinase A |
| Synonyms: |
TBE-1 |
| Locus: |
16q12, 2 |
| Discovery year: |
1989-05-25 |
| Entrez gene record: |
4313 |
| Classification: |
Matrix metallopeptidases |
| Havana BLAST/BLAT: |
OTTHUMG00000133202 |