| Long name: |
MBP Primary Polyclonal Antibody |
| Also known as: |
MBP PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
MBP |
| Specificity: |
This is a highly specific antibody against MBP |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
45-87/167 |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from Guinea Pig MBP |
| Tested Applications: |
IF(IHC-F), IF(IHC-P), IHC-F, IHC-P, WB |
| Recommended dilutions: |
IF(IHC-F)(1:50-200), IF(IHC-P)(1:50-200), IHC-F(1:100-500), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Differential splicing events combined to optional posttranslational modifications give a wide spectrum of isomers, The non classic group of MBP isoforms (isoforms 1 to 3/Golli MBPs) may preferentially have a role in the early developing brain long before myelination, The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis, They have a role in both its formation and stabilization, and may also be involved in signaling pathways in T cells and neural cells, each of them having maybe a specialized function, maybe as components of transcriptional complexes, Oligodendrocyte Marker The classic group of Myelin basic protein (MBP) isoforms (isoforms 4 to 14) are with PLP the most abundant protein components of the myelin membrane in the CNS |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
GDB, Golli MBP, HMBPR, HUGO, Hemopoietic MBP, MBP, MGC99675, MLD, Myelin A1 Protein, Myelin Deficient, Myelin Membrane Encephalitogenic Protein, Myelin basic protien, SHI, SP, Shiverer, MBP_CAVPO, Myelin Basic Protein |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
MBP |
| Short name: |
MBP Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
MBP (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6925 |
| Gene: |
MBP |
More about : MBP |
| Long gene name: |
myelin basic protein |
| Locus: |
18q23 |
| Discovery year: |
1986-01-01 |
| Entrez gene record: |
4155 |
| Pubmed identfication: |
2425357 |
| RefSeq identity: |
NM_001025081 |
| Havana BLAST/BLAT: |
OTTHUMG00000132874 |