| Long name: |
Amyloid Precursor Protein Antibody |
| Also known as: |
Amyloid Precursor Protein Antibody |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Amyloid Precursor Protein |
| Specificity: |
This is a highly specific antibody against Amyloid Precursor Protein |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human APP695 |
| Gene ID number: |
351 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Jul 2008], Multiple transcript variants encoding several different isoforms have been found for this gene, Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy), Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, [provided by RefSeq, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease, This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
A4, A4 amyloid protein, AAA, ABETA, ABPP, AD 1, AD1, APP, APP I, APPI, Alzheimer disease, Alzheimer disease 1, Alzheimer's disease amyloid protein, Amyloid beta A4 precursor protein, Amyloid beta A4 protein, Amyloid beta A4 protein precursor isoform a, Amyloid beta A4 protein precursor isoform b, Amyloid beta A4 protein precursor isoform b, Amyloid beta A4 protein precursor isoform c, Amyloid beta A4 protein precursor isoform c, Amyloid beta protein, Amyloid beta-peptide, Amyloid of aging and alzheimer disease, Beta amyloid peptide, CTFgamma, CVAP, Cerebral vascular amyloid peptide, Human mRNA for amyloid A4 precursor of Alzheimer's disease, PN 2, PN II, PN2, PreA4, Protease nexin II, Soluble APP-beta, Soluble APP-alpha |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Description: |
also called a , is a type of partially differentiated, usually , Precursor cell, blast, blast cell , cell that has lost most or all of the , multipotency, or simply , stem cell , unipotent |
| Gene target: |
Amyloid Precursor Protein |
| Short name: |
Amyloid Protein Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Amyloid Precursor Protein (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
620 |
| Gene: |
APP |
More about : APP |
| Long gene name: |
amyloid beta precursor protein |
| Synonyms gene: |
AD1 |
| Synonyms gene name: |
Alzheimer disease amyloid beta (A4) precursor protein |
| Synonyms name: |
peptidase nexin-II |
| Locus: |
21q21, 3 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
M15533 |
| Entrez gene record: |
351 |
| Pubmed identfication: |
1679289 |
| RefSeq identity: |
NM_000484 |
| Classification: |
Endogenous ligands |
| Havana BLAST/BLAT: |
OTTHUMG00000078438 |
| Locus Specific Databases: |
Alzheimer Disease &, Frontotemporal Dementia Mutation Database |