| Vial description: |
IRS-1, Insulin receptor substrate 1 |
| Category: |
primary antibody |
| Clonality: |
polyclonal |
| Raised in: |
Rabbit |
| Clone: |
1 vial |
| Form: |
Affinity Purified |
| Reactivity: |
Mouse, Rat, Human |
| Purity: |
purified |
| Molecular weight: |
in kDa |
| Source: |
mammalian |
| Activity: |
to be determined |
| Range: |
broad |
| Protein number: |
P35568 |
| Application: |
Western Blot, Immunocytochemistry/Immunofluorescence |
| Storage: |
Avoid freeze/thaw cycles, Upon delivery aliquot and store at -20°, C, C for one year, Shipped at 4° |
| Description: |
Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by acr they should be stored frozen at - 24° |
| Gene target: |
IRS1 |
| Short name: |
anti-IRS1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody to, Antibody |
| Alternative name: |
antibody to-insulin receptor substrate 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
HIRS-1, IRS1 and IDBG-647770 and ENSBTAG00000021308 and 538598, IRS1 and IDBG-82407 and ENSG00000169047 and 3667, Irs1 and IDBG-173589 and ENSMUSG00000055980 and 16367, nuclei, phosphatidylinositol 3-kinase binding, this GO :0002053 and positive regulation of mesenchymal cell proliferation and biological process this GO :0004871 and signal transducer activity and molecular function this GO :0005068 and transmembrane receptor protein tyrosine kinase adaptor activity and molecular function this GO :0005080 and protein kinase C binding and molecular function this GO :0005158 and insulin receptor binding and molecular function this GO :0005159 and insulin-like growth factor receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005899 and insulin receptor complex and cellular component this GO :0005901 and caveola and cellular component this GO :0007165 and signal transduction and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008286 and insulin receptor signaling pathway and biological process this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0010468 and regulation of gene expression and biological process this GO :0010907 and positive regulation of glucose metabolic process and biological process this GO :0014065 and phosphatidylinositol 3-kinase signaling and biological process this GO :0016042 and lipid catabolic process and biological process this GO :0019901 and protein kinase binding and molecular function this GO :0030335 and positive regulation of cell migration and biological process this GO :0030879 and mammary gland development and biological process this GO :0032000 and positive regulation of fatty acid beta-oxidation and biological process this GO :0032868 and response to insulin and biological process this GO :0032869 and cellular response to insulin stimulus and biological process this GO :0034504 and protein localization to nucleus and biological process this GO :0036064 and ciliary basal body and cellular component this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0042169 and SH2 domain binding and molecular function this GO :0042593 and glucose homeostasis and biological process this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0043434 and response to peptide hormone and biological process this GO :0043491 and protein kinase B signaling and biological process this GO :0043548 and phosphatidylinositol 3-kinase binding and molecular function this GO :0043552 and positive regulation of phosphatidylinositol 3-kinase activity and biological process this GO :0045087 and innate immune response and biological process this GO :0045725 and positive regulation of glycogen biosynthetic process and biological process this GO :0046326 and positive regulation of glucose import and biological process this GO :0046627 and negative regulation of insulin receptor signaling pathway and biological process this GO :0046628 and positive regulation of insulin receptor signaling pathway and biological process this GO :0046676 and negative regulation of insulin secretion and biological process this GO :0048009 and insulin-like growth factor receptor signaling pathway and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process this GO :0060397 and JAK-STAT cascade involved in growth hormone signaling pathway and biological process this GO :2001275 and positive regulation of glucose import in response to insulin stimulus and biological process, this GO :0004871 : signal transducer activity, this GO :0004871 : signal transducer activity and also this GO :0005068 : transmembrane receptor protein tyrosine kinase adaptor activity and also this GO :0005080 : protein kinase C binding and also this GO :0005158 : insulin receptor binding and also this GO :0005159 : insulin-like growth factor receptor binding and also this GO :0005515 : protein binding and also this GO :0019901 : protein kinase binding and also this GO :0042169 : SH2 domain binding and also this GO :0043548 : phosphatidylinositol 3-kinase binding, this GO :0005068 : transmembrane receptor protein tyrosine kinase adaptor activity, this GO :0005080 : protein kinase C binding, this GO :0005158 : insulin receptor binding, this GO :0005159 : insulin-like growth factor receptor binding, this GO :0005515 : protein binding, this GO :0019901 : protein kinase binding, this GO :0042169 : SH2 domain binding, this GO :0043548 : phosphatidylinositol 3-kinase binding, insulin receptor substrate 1 |
| Identity: |
6125 |
| Gene: |
IRS1 |
More about : IRS1 |
| Long gene name: |
insulin receptor substrate 1 |
| Synonyms: |
HIRS-1 |
| Locus: |
2q36, 3 |
| Discovery year: |
1992-08-24 |
| Entrez gene record: |
3667 |
| Pubmed identfication: |
1648180 |
| RefSeq identity: |
NM_005544 |
| Classification: |
Pleckstrin homology domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000133179 |