| Long name: |
Estrogen receptor beta Antibody |
| Also known as: |
Estrogen receptor beta Antibody |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Estrogen receptor beta |
| Specificity: |
This is a highly specific antibody against Estrogen receptor beta |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
50-100/530 |
| Subcellular location: |
Nucleus |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ER-Beta |
| Gene ID number: |
2100 |
| Swiss Prot: |
Q92731 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Binds estrogens with an affinity similar to that of ESR1, DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual, Isoform beta-cx lacks ligand binding ability and has no or only very low ere binding activity resulting in the loss of ligand-dependent transactivation ability, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner, Nuclear hormone receptor |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
ER-BETA, ESR-BETA, ESR2, ESRB, ESTRB, Estrogen receptor beta, NR3A2, Nuclear receptor subfamily 3 group A member 2, Erb |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Description: |
2 or 3 and , However, In this sense, When such chemical-signals couple or bind to a receptor, a change in the electrical-activity of a cell, acetylcholine, am olfactory receptor is a protein-molecule that recognizes and responds to , an acetylcholine-receptor recognizes and responds to its endogenous-ligand, chemokinesor cytokines e, e, sometimes in pharmacology, such as enzymes, the term is also used to include other proteins that are drug-targets, they cause some form of cellular/tissue-response, transporters and ion-channels, The receptors are ligand binding factors of type 1, endogenous-chemical signals, g, g, protein-molecules , that receive chemical-signals from outside a cell |
| Gene target: |
Estrogen receptor beta |
| Short name: |
Estrogen receptor beta Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Estrogen receptor b (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3468 |
| Gene: |
ESR2 |
More about : ESR2 |
| Long gene name: |
estrogen receptor 2 |
| Synonyms gene name: |
estrogen receptor 2 (ER beta) |
| Synonyms: |
NR3A2 Erb |
| Synonyms name: |
ER beta |
| Locus: |
14q23, 2-q23, 3 |
| Discovery year: |
1997-01-17 |
| GenBank acession: |
X99101 |
| Entrez gene record: |
2100 |
| Pubmed identfication: |
8769313 |
| Classification: |
Nuclear hormone receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000141306 |