IRS-4 Antibody, ALEXA FLUOR 488

Catalog number:	bs-0187R-A488 Buy Now
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Supplier:	genways bulk
Product name:	IRS-4 Antibody, ALEXA FLUOR 488
Quantity:	bulk
Related search:	irs alexa antibody fluor antibodies signaling insulin role growth

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Long name:	ALEXA FLUOR 488 Conjugated, IRS-4 Polyclonal Antibody
Also known as:	Anti-IRS-4 PAb ALEXA FLUOR 488
Category:	Conjugated Primary Antibodies
Conjugated with:	488, ALEXA FLUOR®
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	IRS-4
Specificity:	This is a highly specific antibody against IRS-4
Modification:	Unmodified
Modification Site:	None
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen range:	420-470/1216
Subcellular location:	Cell membrane
Source:	KLH conjugated synthetic peptide derived from mouse IRS-4
Gene ID Number:	16370
Swiss Prot:	Q9Z0Y7
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse
Cross-reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen:	IGF1R and FGFR1, Interaction with GRB2 enhances insulin-stimulated mitogen-activated protein kinase activity, Involved in the IGF1R mitogenic signaling pathway, May act as negative regulators of the IGF1 signaling pathway by suppressing the function of IRS1 and IRS2, May be involved in nonreceptor tyrosine kinase signaling in myoblasts, May play a role in the signal transduction in response to insulin and to a lesser extent in response to IL4 and GH on mitogenesis, Plays a pivotal role in the proliferation/differentiation of hepatoblastoma cell through EPHB2 activation upon IGF1 stimulation, Plays a role in growth, Promotes the AKT1 signaling pathway and BAD phosphorylation during insulin stimulation without activation of RPS6KB1 or the inhibition of apoptosis, and a complex network of intracellular signaling molecules containing SH2 domains, reproduction and glucose homeostasis, such as insulin receptor, Acts as an interface between multiple growth factor receptors possessing tyrosine kinase activity
Purification:	Purified by Protein A
Storage conditions:	50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission:	499nm/519nm
Synonyms:	PY160 IRS-4
Properties:	ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the IRS-4 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation:	Alexa Fluor
Gene target:	IRS-4
Short name:	IRS-4 Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Label:	ALEXA FLUOR 488
Alternative name:	ALEXA FLUOR 488, IRS-4 (Antibody to)
Alternative technique:	antibodies
Identity:	6128
Gene:	IRS4 | More about : IRS4
Long gene name:	insulin receptor substrate 4
Locus:	Xq22, 3
Discovery year:	1998-11-24
GenBank acession:	AF007567
Entrez gene record:	8471
Pubmed identfication:	9261155 9553137
RefSeq identity:	NM_003604
Havana BLAST/BLAT:	OTTHUMG00000022181
Locus Specific Databases:	Mental Retardation database

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