| Long name: |
Leptin receptor Primary Polyclonal Antibody |
| Also known as: |
Leptin receptor PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Leptin receptorlong |
| Specificity: |
This is a highly specific antibody against Leptin receptorlong |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Leptin receptor |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
An OB-R transcript encodes a soluble form of the receptor, G-CSF receptor, Human OB-R encodes a 1 165 amino acid residue precursor protein with a 22 amino acid residue signal peptide, OB-R binds leptin with high affinity and is a potent leptin antagonist, The transcript was reported to be expressed predominantly in regions of the hypothalamus previously thought to be important in body weight regulation, a 21 amino acid residue transmembrane domain and a 303 amino acid residue cytoplasmic domain, an 816 amino acid residue extracellular domain, and LIF receptor, Leptin receptor (OB-R) is a type I cytokine receptor family protein with significant amino acid sequence identity with gp130 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CD 295, CD295, CD295 antigen, Db, Fa, HuB219, LEP R, LEPR, LEPROT, Leptin receptor fatty, Leptin receptor gene related protein, Leptin receptor precursor, OB R, OB R gene related protein, OB receptor, OB-RGRP, Obr, obl |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene: |
LEPR |
More about : LEPR |
| Description: |
2 or 3 and , However, In this sense, When such chemical-signals couple or bind to a receptor, a change in the electrical-activity of a cell, acetylcholine, am olfactory receptor is a protein-molecule that recognizes and responds to , an acetylcholine-receptor recognizes and responds to its endogenous-ligand, chemokinesor cytokines e, e, sometimes in pharmacology, such as enzymes, the term is also used to include other proteins that are drug-targets, they cause some form of cellular/tissue-response, transporters and ion-channels, The receptors are ligand binding factors of type 1, endogenous-chemical signals, g, g, protein-molecules , that receive chemical-signals from outside a cell |
| Gene target: |
Leptin receptor |
| Short name: |
Leptin receptor Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Leptin receptor (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6554 |
| Long gene name: |
leptin receptor |
| Synonyms: |
OBR CD295 |
| Locus: |
1p31, 3 |
| Discovery year: |
1996-05-09 |
| GenBank acession: |
U43168 |
| Entrez gene record: |
3953 |
| Pubmed identfication: |
8548812 8812446 |
| RefSeq identity: |
NM_002303 |
| Classification: |
CD molecules Immunoglobulin like domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000009115 |
| Locus Specific Databases: |
LRG_283 |