| Long name: |
M2-PK Primary Polyclonal Antibody |
| Also known as: |
M2-PK PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
PKM2 |
| Specificity: |
This is a highly specific antibody against PKM2 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
70-120/531 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human M2-PK |
| Gene ID number: |
5315 |
| Swiss Prot: |
P14618 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Plays a general role in caspase independent cell death of tumor cells, Stimulates POU5F1-mediated transcriptional activation, The ratio betwween the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production, The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival, generating ATP, Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CTHBP, Cytosolic thyroid hormone-binding protein, HEL-S-30, OIP-3, OIP3, Opa-interacting protein 3, PK2, PKM, PKM2, Pyruvate kinase 2/3, Pyruvate kinase PKM, Pyruvate kinase muscle isozyme, TCB, THBP1, Thyroid hormone-binding protein 1, Tumor M2-PK, p58, PK3 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
M2-PK |
| Short name: |
M2-PK Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
M2-PK (Antibody to) |
| Alternative technique: |
antibodies |