| Long name: |
Caspase 3 Primary Polyclonal Antibody |
| Also known as: |
Caspase 3 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Caspase-3 |
| Specificity: |
This is a highly specific antibody against Caspase-3 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
60-100/277 |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Caspase 3(Active) |
| Gene ID number: |
836 |
| Swiss Prot: |
P42574 |
| Tested Applications: |
FCM, IF(ICC), IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
FCM(1:20-100), IF(ICC)(1:50-200), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Bovine, Goat, Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
-7 and -9, At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond, Cleaves and activates caspase-6, Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain, Involved in the cleavage of huntingtin, Triggers cell adhesion in sympathetic neurons through RET cleavage, Involved in the activation cascade of caspases responsible for apoptosis execution |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Apopain, CASP-3, CASP3, CPP-32, CPP32B, Caspase-3, Cysteine protease CPP32, Protein Yama, SCA-1, SREBP cleavage activity 1, CPP32 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Caspase 3 |
| Short name: |
Caspase 3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
caspase 3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
43777 |
| Gene: |
CASP1P3 |
More about : CASP1P3 |
| Long gene name: |
caspase 1 pseudogene 3 |
| Synonyms gene name: |
apoptosis-related cysteine peptidase pseudogene 3 , caspase 1 |
| Locus: |
11q22, 3 |
| Discovery year: |
2012-02-24 |
| Entrez gene record: |
100422634 |
| RefSeq identity: |
NG_024409 |