| Category: |
Proteins And Peptides |
| Target: |
TP53 Regulated Inhibitor Of Apoptosis 1 Protein |
| Immunogen: |
See techfile |
| Reactivity: |
Mouse, Rat, Human |
| Form: |
Unconjugated |
| Purification: |
Affinity purified |
| Applications: |
WB (for other see techfile or inquire) |
| Stock availability: |
Shipped within 5-10 working days |
| Storage conditions: |
Avoid repeated freeze/thaw cycles, Aliquot and store at -20 °, C |
| Warnings: |
This product is for research use only |
| Description: |
Not all receptor antagonist that bind to enzymes are inhibitors, Since blocking an enzyme's activity can kill a pathogen , activator, caspase, esterase inhibitors , lipoprotein, many drugs are enzyme inhibitors, papain, pathway, peptidase, protease , proteinase, trypsin, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme, , Tissue, acrosin, activity, and decreases its , are , bind to enzymes and increase their , enzymatic activity, enzyme activator ligands or agonists , enzyme receptor , imbalance, metabolic , or correct a , or receptor ligands or receptor antagonists that bind to an , proteins |
| Source: |
proteins, Recombinants or rec |
| Group: |
recombinants |
| Gene target: |
TP53 Regulated Inhibitor Of 1 Protein |
| Short name: |
Anti-TP53 Regulated Inhibitor Of Apoptosis 1 Protein (Recombinant) |
| Technique: |
E, abbex advises they will be reconstituted in a buffer soluion or culture medium for cell culture, coli recombinant proteins are , supplied as white sterile powder lyopillized, Recombinant, genetic recombinations , in Escherichia coli |
| Alternative name: |
antibody to-tumor protein p53 Regulated suppressor on programmed cellular destruction 1 Protein (recombinant) |
| Alternative technique: |
rec |
| Alternative to gene target: |
BCC7 and LFS1 and P53 and TRP53, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0006461 and protein complex assembly and biological process this GO :0006915 and apoptotic process and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0006977 and DNA damage response, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046677 and response to antibiotic and biological process this GO :0046872 and metal ion binding and molecular function this GO :0046902 and regulation of mitochondrial membrane permeability and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0047485 and protein N-terminus binding and molecular function this GO :0048147 and negative regulation of fibroblast proliferation and biological process this GO :0048568 and embryonic organ development and biological process this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0051087 and chaperone binding and molecular function this GO :0051097 and negative regulation of helicase activity and biological process this GO :0051262 and protein tetramerization and biological process this GO :0051276 and chromosome organization and biological process this GO :0051402 and neuron apoptotic process and biological process this GO :0051721 and protein phosphatase 2A binding and molecular function this GO :0051726 and regulation of cell cycle and biological process this GO :0070243 and regulation of thymocyte apoptotic process and biological process this GO :0070245 and positive regulation of thymocyte apoptotic process and biological process this GO :0070266 and necroptotic process and biological process this GO :0071158 and positive regulation of cell cycle arrest and biological process this GO :0071456 and cellular response to hypoxia and biological process this GO :0071479 and cellular response to ionizing radiation and biological process this GO :0071850 and mitotic cell cycle arrest and biological process this GO :0072332 and intrinsic apoptotic signaling pathway by p53 class mediator and biological process this GO :0090200 and positive regulation of release of cytochrome c from mitochondria and biological process this GO :0090343 and positive regulation of cell aging and biological process this GO :0090399 and replicative senescence and biological process this GO :0090403 and oxidative stress-induced premature senescence and biological process this GO :0097193 and intrinsic apoptotic signaling pathway and biological process this GO :0097252 and oli this GO dendrocyte apoptotic process and biological process this GO :0097371 and MDM2/MDM4 family protein binding and molecular function this GO :1900740 and positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway and biological process this GO :1901525 and negative regulation of macromitophagy and biological process this GO :1902108 and regulation of mitochondrial membrane permeability involved in apoptotic process and biological process this GO :2000378 and negative regulation of reactive oxygen species metabolic process and biological process this GO :2000379 and positive regulation of reactive oxygen species metabolic process and biological process this GO :2001244 and positive regulation of intrinsic apoptotic signaling pathway and biological process, MDM2/MDM4 family protein binding, TP53 and IDBG-26364 and ENSG00000141510 and 7157, TP53 and IDBG-635147 and ENSBTAG00000001069 and 281542, Trp53 and IDBG-191036 and ENSMUSG00000059552 and 22059, nuclei, signal transduction by p53 class mediator and biological process this GO :0030512 and negative regulation of transforming growth factor beta receptor signaling pathway and biological process this GO :0030971 and receptor tyrosine kinase binding and molecular function this GO :0031065 and positive regulation of histone deacetylation and biological process this GO :0031497 and chromatin assembly and biological process this GO :0031571 and mitotic G1 DNA damage checkpoint and biological process this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0032461 and positive regulation of protein oli this GO merization and biological process this GO :0033077 and T cell differentiation in thymus and biological process this GO :0034103 and regulation of tissue remodeling and biological process this GO :0034613 and cellular protein localization and biological process this GO :0034644 and cellular response to UV and biological process this GO :0035033 and histone deacetylase regulator activity and molecular function this GO :0035035 and histone acetyltransferase binding and molecular function this GO :0035264 and multicellular organism growth and biological process this GO :0035690 and cellular response to drug and biological process this GO :0035794 and positive regulation of mitochondrial membrane permeability and biological process this GO :0042127 and regulation of cell proliferation and biological process this GO :0042149 and cellular response to glucose starvation and biological process this GO :0042493 and response to drug and biological process this GO :0042771 and intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator and biological process this GO :0042802 and identical protein binding and molecular function this GO :0042981 and regulation of apoptotic process and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043234 and protein complex and cellular component this GO :0043523 and regulation of neuron apoptotic process and biological process this GO :0043525 and positive regulation of neuron apoptotic process and biological process this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045892 and negative regulation of transcription, signal transduction by p53 class mediator resulting in cell cycle arrest and biological process this GO :0006978 and DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator and biological process this GO :0006979 and response to oxidative stress and biological process this GO :0006983 and ER overload response and biological process this GO :0007049 and cell cycle and biological process this GO :0007050 and cell cycle arrest and biological process this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0007219 and Notch signaling pathway and biological process this GO :0007265 and Ras protein signal transduction and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0007369 and gastrulation and biological process this GO :0007406 and negative regulation of neuroblast proliferation and biological process this GO :0007417 and central nervous system development and biological process this GO :0007569 and cell aging and biological process this GO :0007596 and blood coagulation and biological process this GO :0008104 and protein localization and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0008156 and negative regulation of DNA replication and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0008283 and cell proliferation and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0008340 and determination of adult lifespan and biological process this GO :0009303 and rRNA transcription and biological process this GO :0009411 and response to UV and biological process this GO :0009651 and response to salt stress and biological process this GO :0009792 and embryo development ending in birth or egg hatching and biological process this GO :0010165 and response to X-ray and biological process this GO :0010332 and response to gamma radiation and biological process this GO :0010666 and positive regulation of cardiac muscle cell apoptotic process and biological process this GO :0016032 and viral process and biological process this GO :0016363 and nuclear matrix and cellular component this GO :0016604 and nuclear body and cellular component this GO :0016605 and PML body and cellular component this GO :0019899 and enzyme binding and molecular function this GO :0019901 and protein kinase binding and molecular function this GO :0019903 and protein phosphatase binding and molecular function this GO :0021549 and cerebellum development and biological process this GO :0030154 and cell differentiation and biological process this GO :0030308 and negative regulation of cell growth and biological process this GO :0030330 and DNA damage response, this GO :0000060 and protein import into nucleus, this GO :0000979 : RNA polymerase II core promoter sequence-specific DNA binding, this GO :0000979 : RNA polymerase II core promoter sequence-specific DNA binding and also this GO :0001077 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and also this GO :0001085 : RNA polymerase II transcription factor binding and also this GO :0001228 : RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and also this GO :0002020 : protease binding and also this GO :0002039 : p53 binding and also this GO :0003677 : DNA binding and also this GO :0003682 : chromatin binding and also this GO :0003684 : damaged DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0005507 : copper ion binding and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0008134 : transcription factor binding and also this GO :0008270 : zinc ion binding and also this GO :0019899 : enzyme binding and also this GO :0019901 : protein kinase binding and also this GO :0019903 : protein phosphatase binding and also this GO :0030971 : receptor tyrosine kinase binding and also this GO :0031625 : ubiquitin protein ligase binding and also this GO :0035033 : histone deacetylase regulator activity and also this GO :0035035 : histone acetyltransferase binding and also this GO :0042802 : identical protein binding and also this GO :0044212 : transcription regulatory region DNA binding and also this GO :0046872 : metal ion binding and also this GO :0046982 : protein heterodimerization activity and also this GO :0047485 : protein N-terminus binding and also this GO :0051087 : chaperone binding and also this GO :0051721 : protein phosphatase 2A binding and also this GO :0097371 : MDM2/MDM4 family protein binding, this GO :0001077 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, this GO :0001085 : RNA polymerase II transcription factor binding, this GO :0001228 : RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, this GO :0002020 : protease binding, this GO :0002039 : p53 binding, this GO :0003677 : DNA binding, this GO :0003682 : chromatin binding, this GO :0003684 : damaged DNA binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0005507 : copper ion binding, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0008134 : transcription factor binding, this GO :0008270 : zinc ion binding, this GO :0019899 : enzyme binding, this GO :0019901 : protein kinase binding, this GO :0019903 : protein phosphatase binding, this GO :0030971 : receptor tyrosine kinase binding, this GO :0031625 : ubiquitin protein ligase binding, this GO :0035033 : histone deacetylase regulator activity, this GO :0035035 : histone acetyltransferase binding, this GO :0042802 : identical protein binding, this GO :0044212 : transcription regulatory region DNA binding, this GO :0046872 : metal ion binding, this GO :0046982 : protein heterodimerization activity, this GO :0047485 : protein N-terminus binding, this GO :0051087 : chaperone binding, this GO :0051721 : protein phosphatase 2A binding, this GO :0097371 : MDM2/MDM4 family protein binding, translocation and biological process this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000733 and DNA strand renaturation and biological process this GO :0000785 and chromatin and cellular component this GO :0000790 and nuclear chromatin and cellular component this GO :0000979 and RNA polymerase II core promoter sequence-specific DNA binding and molecular function this GO :0001077 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0001085 and RNA polymerase II transcription factor binding and molecular function this GO :0001228 and RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0001701 and in utero embryonic development and biological process this GO :0001756 and somitogenesis and biological process this GO :0001836 and release of cytochrome c from mitochondria and biological process this GO :0002020 and protease binding and molecular function this GO :0002039 and p53 binding and molecular function this GO :0002309 and T cell proliferation involved in immune response and biological process this GO :0002326 and B cell lineage commitment and biological process this GO :0002360 and T cell lineage commitment and biological process this GO :0002931 and response to ischemia and biological process this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0003684 and damaged DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005507 and copper ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005657 and replication fork and cellular component this GO :0005669 and transcription factor TFIID complex and cellular component this GO :0005730 and nucleolus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005759 and mitochondrial matrix and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005829 and cytosol and cellular component this GO :0006284 and base-excision repair and biological process this GO :0006289 and nucleotide-excision repair and biological process this GO :0006302 and double-strand break repair and biological process this GO :0006351 and transcription, tumor protein p53 |
| Identity: |
11998 |
| Gene: |
TP53 |
More about : TP53 |
| Long gene name: |
tumor protein p53 |
| Synonyms: |
p53 LFS1 |
| Synonyms name: |
Li-Fraumeni syndrome |
| Locus: |
17p13, 1 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
AF307851 |
| Entrez gene record: |
7157 |
| Pubmed identfication: |
6396087 3456488 2047879 |
| RefSeq identity: |
NM_000546 |
| Havana BLAST/BLAT: |
OTTHUMG00000162125 |
| Locus Specific Databases: |
IARC TP53 Mutation Database p53 UMD TP53 mutation database Database of Germline p53 Mutations MUTP53LOAD, Mutant p53 Loss Of Activity Database LRG_321 |