| Alternative name 1: |
Clone: MEC 8D3, FITC, Rat Mab anti-Mouse, Transferrin Receptor, CD70 |
| Alternative name 2: |
Clone: MEC 8D3, FITC, Rat Mab antibody-Mouse, Transferrin Receptor, CD70 |
| Alternative name 3: |
Clone: MEC 8D3, FITC, Rattus norvegicus Mab antibody-Mus musculus, Transferrin Receptor, CD70 |
| Alternative name 4: |
anti-CD70 Transferrin Receptor Clone: MEC 8D3 |
| Alternative name 5: |
CD70 Transferrin Receptor Clone: MEC 8D3 |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| Properties: |
FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, When excited at 488 nanometers, accurate-monoclonals FITC is highly sensitive to pH extremes, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, This accurate-monoclonals Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS |
| Conjugation: |
Anti-FITC Antibody |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Rats are used to make rat monoclonal anti mouse antibodies, Rats , There are less rat- than mouse clones however, Monoclonals of this antigen are available in different clones, Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats, genes from rodents , of the genus |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Rattus norvegicus, Mus musculus |
| French translation: |
anticorps |
| Gene target: |
MEC 8D3, Monoclonal, Transferrin Receptor, CD70 |
| Short name: |
Clone: MEC 8D3, FITC, Mouse Monoclonal antibody-Mouse, Transferrin Receptor, CD70 |
| Technique: |
Fluorescein, Monoclonals or monoclonal antibodies, mouses, Mouse |
| Host: |
Rat |
| Label: |
FITC |
| Species: |
Mouses, Rats, Mouse |
| Alternative name: |
Rat Mouse monoclonal (Antibody to)-Mouse, Transferrin Receptor, clonality: MEC 8D3, fluorecein, CD70 molecule |
| Alternative technique: |
murine |
| Alternative to gene target: |
CD27L and CD27LG and TNFSF7, CD70 and IDBG-21699 and ENSG00000125726 and 970, CD70 and IDBG-643945 and ENSBTAG00000009752 and 522074, Cd70 and IDBG-193725 and ENSMUSG00000019489 and 21948, Extracellular, protein binding, this GO :0002020 and protease binding and molecular function this GO :0005102 and receptor binding and molecular function this GO :0005125 and cytokine activity and molecular function this GO :0005164 and tumor necrosis factor receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006955 and immune response and biological process this GO :0007165 and signal transduction and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0008283 and cell proliferation and biological process this GO :0016020 and membrane and cellular component this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0097191 and extrinsic apoptotic signaling pathway and biological process, this GO :0002020 : protease binding, this GO :0002020 : protease binding and also this GO :0005102 : receptor binding and also this GO :0005125 : cytokine activity and also this GO :0005164 : tumor necrosis factor receptor binding and also this GO :0005515 : protein binding, this GO :0005102 : receptor binding, this GO :0005125 : cytokine activity, this GO :0005164 : tumor necrosis factor receptor binding, this GO :0005515 : protein binding, CD70 molecule |
| Identity: |
11937 |
| Gene: |
CD70 |
More about : CD70 |
| Long gene name: |
CD70 molecule |
| Synonyms gene: |
CD27LG TNFSF7 |
| Synonyms gene name: |
member 7 , tumor necrosis factor (ligand) superfamily |
| Synonyms: |
CD27L |
| Locus: |
19p13, 3 |
| Discovery year: |
1993-11-08 |
| GenBank acession: |
L08096 |
| Entrez gene record: |
970 |
| Pubmed identfication: |
8387892 8120384 |
| Classification: |
Tumor necrosis factor superfamily CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000181834 |