| Gene Name: |
PRAME |
| Species Reactivity: |
Human (Homo sapiens) |
| Synonyms: |
CT130 |
| Uniprot: |
P78395 |
| Description: |
this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, Properly used, This is a highly purified antibody with strong binding affinity towards the antigen that it has been risen against |
| Storage and handling: |
Generally, Reconstituted lyophilised and antibodies in liquid form can be shipped and stored for short terms at +4 degrees Celsius, it is recomended for long term storage (up to one year) 25-50% glycerol or ethylene glycol to be added and the vial must be stored at -20°, C, Lyophilized antibodies can be shipped at ambient temperature and stored for short terms at +4 degrees Celsius and at -20 for long term storage |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of the antibodies unchanged |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp |
| Gene target: |
PRAME |
| Short name: |
Anti- PRAME |
| Species: |
Humans, Human |
| Alternative name: |
sapiens preferentially expressed antigen in melanoma, antibody to-H |
| Alternative to gene target: |
CT130 and MAPE and OIP-4 and OIP4, DNA-templated and biological process this GO :0006915 and apoptotic process and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0030154 and cell differentiation and biological process this GO :0040008 and regulation of growth and biological process this GO :0042974 and retinoic acid receptor binding and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0045596 and negative regulation of cell differentiation and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0048387 and negative regulation of retinoic acid receptor signaling pathway and biological process, PRAME and IDBG-2240 and ENSG00000185686 and 23532, nuclei, retinoic acid receptor binding, this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006351 and transcription, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0042974 : retinoic acid receptor binding, this GO :0042974 : retinoic acid receptor binding, preferentially expressed antigen in melanoma |
| Identity: |
9336 |
| Gene: |
PRAME |
More about : PRAME |
| Long gene name: |
preferentially expressed antigen in melanoma |
| Synonyms gene: |
MAPE |
| Synonyms name: |
cancer/testis antigen 130 |
| Locus: |
22q11, 22 |
| Discovery year: |
1996-06-21 |
| GenBank acession: |
U65011 |
| Entrez gene record: |
23532 |
| Pubmed identfication: |
9047241 10591208 |
| RefSeq identity: |
NM_206953 |
| Classification: |
PRAME family |
| Havana BLAST/BLAT: |
OTTHUMG00000151172 |