| Reacts with: |
Human |
| Source: |
proteins, Recombinants or rec |
| Description: |
Recombinant Human Vascular Endothelial Growth Factor Receptor 2 is produced by our Mammalian expression system and the target gene encoding Ala20-Glu764 is expressed with a Fc tag at the C-terminus |
| Molecular Weight: |
110, 4 kD |
| UniProt number: |
P35968 |
| State of the product: |
Freeze-dried |
| Shipping conditions: |
Ambient temperature |
| Formulation: |
2 um filtered solution of phosphate buffered saline, 4, Lyophilized from a 0, pH7 |
| Storage recommendations: |
-20°, Aliquots of reconstituted samples are stable at less -20°, If kept at at room temperature, If kept at at room temperature, Reconstituted protein solution should be stored at 4-7°, it is stable for 3 weeks, it is stable for 3 weeks, C, C for 2-7 days, C for 3 months, Freeze-dried proteins should be stored frozen at < |
| Reconstitution: |
Dissolve the lyophilized protein in ddH2O, Do not mix by vortex or pipetting, It is not recommended to reconstitute to a concentration less than 100 &mu, Please aliquot the reconstituted solution to minimize freeze-thaw cycles, Always centrifuge tubes before opening, g/ml |
| Purity: |
and determined by Polyacrylamide gel electrophoresis, Greater than 95% |
| Sequence of the amino acid: |
ASVGLPSVSLDLPRLSIQKDILTIKANTTLQITCRGQRDLDWLWPNNQSGSEQRVEVTECSDGLFCKTLTIPKVIGNDTGAYKCFYRETDLASVIYVYVQDYRSPFIASVSDQHGVVYITENKNKTVVIPCLGSISNLNVSLCARYPEKRFVPDGNRISWDSKKGFTIPSYMISYAGMVFCEAKINDESYQSIMYIVVVVGYRIYDVVLSPSHGIELSVGEKLVLNCTARTELNVGIDFNWEYPSSKHQHKKLVNRDLKTQSGSEMKKFLSTLTIDGITRSDQGLYTCAASSGLMTKKNSTFVRVHEKPFVAFGSGMESLVEATVGERVRIPAKYLGYPPPEIKWYKNGIPLESNHTIKAGHVLTIMEVSERDTGNYTVILTNPISKEKQSHVVSLVVYVPPQIGEKSLISPVDSYQYGTTQTLTCTVYAIPPPHHIHWYWQLEEECANEPSHAVSVTNPYPCEEWRSVEDFQGGNKIEVNKNQFALIEGKNKTVSTLVIQAANVSALYKCEAVNKVGRGERVISFHVTRGPEITLQPDMQPTEQESVSLWCTADRSTFENLTWYKLGPQPLPIHVGELPTPVCKNLDTLWKLNATMFSNSTNDILIMELKNASLQDQGDYVCLAQDRKTKKRHCVVRQLTVLERVAPTITGNLENQTTSIGESIEVSCTASGNPPPQIMWFKDNETLVEDSGIVLKDGNRNLTIRRVRKEDEGLYTCQACSVLGCAKVEAFFIIEGAQEKTNLEVDDIEGRMDEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK |
| Levels of endotoxin: |
11 IEU/ug, LAL test shows less than than 0 |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp |
| Group: |
recombinants |
| Gene target: |
FLK-1, KDR (C-Fc), VEGF R2, VEGF Receptor 2 |
| Short name: |
FLK-1, KDR (C-Fc), VEGF R2, Recombinant VEGF Receptor 2 |
| Technique: |
E, coli recombinant proteins are , novo advises they will be reconstituted in a buffer soluion or culture medium for cell culture, supplied as white sterile powder lyopillized, Recombinant, genetic recombinations , in Escherichia coli |
| Species: |
Humans, Human |
| Alternative name: |
FLK-1, VEGF R2, kinase insert domain receptor (a type III receptor tyrosine kinase) (C-fragment c), sapiens VEGF Receptor 2, recombinant H |
| Alternative technique: |
rec |
| Alternative to gene target: |
CD309 and FLK1 and VEGFR and VEGFR2, KDR and IDBG-19161 and ENSG00000128052 and 3791, KDR and IDBG-642352 and ENSBTAG00000000782 and 407170, Kdr and IDBG-172240 and ENSMUSG00000062960 and 16542, nuclei, this GO :0001525 and angiogenesis and biological process this GO :0001541 and ovarian follicle development and biological process this GO :0001570 and vasculogenesis and biological process this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0001938 and positive regulation of endothelial cell proliferation and biological process this GO :0001945 and lymph vessel development and biological process this GO :0002042 and cell migration involved in sprouting angiogenesis and biological process this GO :0002053 and positive regulation of mesenchymal cell proliferation and biological process this GO :0003158 and endothelium development and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004714 and transmembrane receptor protein tyrosine kinase activity and molecular function this GO :0004716 and receptor signaling protein tyrosine kinase activity and molecular function this GO :0005021 and vascular endothelial growth factor-activated receptor activity and molecular function this GO :0005178 and integrin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005634 and nucleus and cellular component this GO :0005768 and endosome and cellular component this GO :0005769 and early endosome and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0007169 and transmembrane receptor protein tyrosine kinase signaling pathway and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008360 and regulation of cell shape and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0010595 and positive regulation of endothelial cell migration and biological process this GO :0014068 and positive regulation of phosphatidylinositol 3-kinase signaling and biological process this GO :0016023 and cytoplasmic membrane-bounded vesicle and cellular component this GO :0016032 and viral process and biological process this GO :0016477 and cell migration and biological process this GO :0016772 and transferase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0004714 : transmembrane receptor protein tyrosine kinase activity and also this GO :0004716 : receptor signaling protein tyrosine kinase activity and also this GO :0005021 : vascular endothelial growth factor-activated receptor activity and also this GO :0005178 : integrin binding and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0004714 : transmembrane receptor protein tyrosine kinase activity, this GO :0004716 : receptor signaling protein tyrosine kinase activity, this GO :0005021 : vascular endothelial growth factor-activated receptor activity, this GO :0005178 : integrin binding, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, this GO :0019838 : growth factor binding, this GO :0038085 : vascular endothelial growth factor binding, this GO :0051879 : Hsp90 protein binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0019838 : growth factor binding and also this GO :0038085 : vascular endothelial growth factor binding and also this GO :0051879 : Hsp90 protein binding, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0019838 and growth factor binding and molecular function this GO :0023014 and signal transduction by phosphorylation and biological process this GO :0030054 and cell junction and cellular component this GO :0030097 and hemopoiesis and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0030324 and lung development and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0035162 and embryonic hemopoiesis and biological process this GO :0035584 and calcium-mediated signaling using intracellular calcium source and biological process this GO :0035924 and cellular response to vascular endothelial growth factor stimulus and biological process this GO :0038083 and peptidyl-tyrosine autophosphorylation and biological process this GO :0038084 and vascular endothelial growth factor signaling pathway and biological process this GO :0038085 and vascular endothelial growth factor binding and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043129 and surfactant homeostasis and biological process this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0045121 and membrane raft and cellular component this GO :0045165 and cell fate commitment and biological process this GO :0045446 and endothelial cell differentiation and biological process this GO :0045766 and positive regulation of angiogenesis and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0048010 and vascular endothelial growth factor receptor signaling pathway and biological process this GO :0048286 and lung alveolus development and biological process this GO :0048469 and cell maturation and biological process this GO :0048754 and branching morphogenesis of an epithelial tube and biological process this GO :0050679 and positive regulation of epithelial cell proliferation and biological process this GO :0050927 and positive regulation of positive chemotaxis and biological process this GO :0051770 and positive regulation of nitric-oxide synthase biosynthetic process and biological process this GO :0051879 and Hsp90 protein binding and molecular function this GO :0051894 and positive regulation of focal adhesion assembly and biological process this GO :0055074 and calcium ion homeostasis and biological process this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0071944 and cell periphery and cellular component this GO :0097443 and sorting endosome and cellular component this GO :2000352 and negative regulation of endothelial cell apoptotic process and biological process this GO :2001214 and positive regulation of vasculogenesis and biological process, kinase insert domain receptor (a type III receptor tyrosine kinase) |
| Identity: |
12680 |
| Gene: |
VEGFA |
More about : VEGFA |
| Long gene name: |
vascular endothelial growth factor A |
| Synonyms gene: |
VEGF |
| Synonyms gene name: |
vascular endothelial growth factor |
| Synonyms: |
VEGF-A VPF |
| Locus: |
6p21, 1 |
| Discovery year: |
1994-01-10 |
| GenBank acession: |
AB021221 |
| Entrez gene record: |
7422 |
| Pubmed identfication: |
8786112 |
| RefSeq identity: |
NM_001025366 |
| Classification: |
VEGF family |
| Havana BLAST/BLAT: |
OTTHUMG00000014745 |
| Locus Specific Databases: |
ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database |