| Reacts with: |
Human |
| Source: |
proteins, Recombinants or rec |
| Description: |
Recombinant Human Serpin A8/Angiotensinogen is produced by our Mammalian expression system and the target gene encoding Asp34-Ala485 is expressed with a 6His tag at the C-terminus |
| Molecular Weight: |
51, 7 kD |
| UniProt number: |
P01019 |
| State of the product: |
Liquid |
| Shipping conditions: |
Dry Ice/ice packs |
| Formulation: |
150 mM sodium chloride, 2 um filtered solution of 20 mM PB, 4, Supplied as a 0, pH7 |
| Storage recommendations: |
-20°, Please minimize freeze-thaw cycles, stable for 6 months after receipt, C, Store at < |
| Reconstitution: |
Dissolve the lyophilized protein in ddH2O, Do not mix by vortex or pipetting, It is not recommended to reconstitute to a concentration less than 100 &mu, Please aliquot the reconstituted solution to minimize freeze-thaw cycles, Always centrifuge tubes before opening, g/ml |
| Purity: |
and determined by Polyacrylamide gel electrophoresis, Greater than 95% |
| Sequence of the amino acid: |
DRVYIHPFHLVIHNESTCEQLAKANAGKPKDPTFIPAPIQAKTSPVDEKALQDQLVLVAAKLDTEDKLRAAMVGMLANFLGFRIYGMHSELWGVVHGATVLSPTAVFGTLASLYLGALDHTADRLQAILGVPWKDKNCTSRLDAHKVLSALQAVQGLLVAQGRADSQAQLLLSTVVGVFTAPGLHLKQPFVQGLALYTPVVLPRSLDFTELDVAAEKIDRFMQAVTGWKTGCSLTGASVDSTLAFNTYVHFQGKMKGFSLLAEPQEFWVDNSTSVSVPMLSGMGTFQHWSDIQDNFSVTQVSFTESACLLLIQPHYASDLDKVEGLTFQQNSLNWMKKLSPRTIHLTMPQLVLQGSYDLQDLLAQAELPAILHTELNLQKLSNDRIRVGEVLNSIFFELEADEREPTESTQQLNKPEVLEVTLNRPFLFAVYDQSATALHFLGRVANPLSTAVDHHHHHH |
| Levels of endotoxin: |
11 IEU/ug, LAL test shows less than than 0 |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp |
| Group: |
recombinants |
| Gene target: |
AGT (C-6His), Serpin A8, Angiotensinogen |
| Short name: |
AGT (C-6His), Serpin A8, Recombinant Angiotensinogen |
| Technique: |
E, coli recombinant proteins are , novo advises they will be reconstituted in a buffer soluion or culture medium for cell culture, supplied as white sterile powder lyopillized, Recombinant, genetic recombinations , in Escherichia coli |
| Species: |
Humans, Human |
| Alternative name: |
Serpin A8, angiotensinogen (serpin peptidase inhibitor, clade A, member 8) (C-6His), sapiens Angiotensinogen, recombinant H |
| Alternative technique: |
rec |
| Alternative to gene target: |
AGT and IDBG-107363 and ENSG00000135744 and 183, AGT and IDBG-632058 and ENSBTAG00000012393 and 527114, ANHU and SERPINA8, Agt and IDBG-200169 and ENSMUSG00000031980 and 11606, DNA-templated and biological process this GO :0045909 and positive regulation of vasodilation and biological process this GO :0046622 and positive regulation of organ growth and biological process this GO :0048143 and astrocyte activation and biological process this GO :0048144 and fibroblast proliferation and biological process this GO :0048146 and positive regulation of fibroblast proliferation and biological process this GO :0048169 and regulation of long-term neuronal synaptic plasticity and biological process this GO :0048659 and smooth muscle cell proliferation and biological process this GO :0050663 and cytokine secretion and biological process this GO :0050727 and regulation of inflammatory response and biological process this GO :0050729 and positive regulation of inflammatory response and biological process this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0051145 and smooth muscle cell differentiation and biological process this GO :0051387 and negative regulation of neurotrophin TRK receptor signaling pathway and biological process this GO :0051403 and stress-activated MAPK cascade and biological process this GO :0051924 and regulation of calcium ion transport and biological process this GO :0051969 and regulation of transmission of nerve impulse and biological process this GO :0061049 and cell growth involved in cardiac muscle cell development and biological process this GO :0061098 and positive regulation of protein tyrosine kinase activity and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070371 and ERK1 and ERK2 cascade and biological process this GO :0070471 and uterine smooth muscle contraction and biological process this GO :0071260 and cellular response to mechanical stimulus and biological process this GO :0072562 and blood microparticle and cellular component this GO :0090190 and positive regulation of branching involved in ureteric bud morphogenesis and biological process this GO :2000379 and positive regulation of reactive oxygen species metabolic process and biological process this GO :2001238 and positive regulation of extrinsic apoptotic signaling pathway and biological process, Extracellular, clade A, member 8), this GO :0001543 and ovarian follicle rupture and biological process this GO :0001558 and regulation of cell growth and biological process this GO :0001568 and blood vessel development and biological process this GO :0001658 and branching involved in ureteric bud morphogenesis and biological process this GO :0001819 and positive regulation of cytokine production and biological process this GO :0001822 and kidney development and biological process this GO :0001974 and blood vessel remodeling and biological process this GO :0001991 and regulation of systemic arterial blood pressure by circulatory renin-angiotensin and biological process this GO :0001998 and angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure and biological process this GO :0001999 and renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure and biological process this GO :0002003 and angiotensin maturation and biological process this GO :0002016 and regulation of blood volume by renin-angiotensin and biological process this GO :0002018 and renin-angiotensin regulation of aldosterone production and biological process this GO :0002019 and regulation of renal output by angiotensin and biological process this GO :0002034 and regulation of blood vessel size by renin-angiotensin and biological process this GO :0002035 and brain renin-angiotensin system and biological process this GO :0003014 and renal system process and biological process this GO :0003051 and angiotensin-mediated drinking behavior and biological process this GO :0003331 and positive regulation of extracellular matrix constituent secretion and biological process this GO :0004867 and serine-type endopeptidase inhibitor activity and molecular function this GO :0005179 and hormone activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006883 and cellular sodium ion homeostasis and biological process this GO :0007160 and cell-matrix adhesion and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007199 and G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger and biological process this GO :0007200 and phospholipase C-activating G-protein coupled receptor signaling pathway and biological process this GO :0007202 and activation of phospholipase C activity and biological process this GO :0007250 and activation of NF-kappaB-inducing kinase activity and biological process this GO :0007263 and nitric oxide mediated signal transduction and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0007565 and female pregnancy and biological process this GO :0007568 and aging and biological process this GO :0007588 and excretion and biological process this GO :0008065 and establishment of blood-nerve barrier and biological process this GO :0008083 and growth factor activity and molecular function this GO :0008217 and regulation of blood pressure and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009409 and response to cold and biological process this GO :0009651 and response to salt stress and biological process this GO :0010468 and regulation of gene expression and biological process this GO :0010535 and positive regulation of activation of JAK2 kinase activity and biological process this GO :0010595 and positive regulation of endothelial cell migration and biological process this GO :0010613 and positive regulation of cardiac muscle hypertrophy and biological process this GO :0010628 and positive regulation of gene expression and biological process this GO :0010744 and positive regulation of macrophage derived foam cell differentiation and biological process this GO :0010873 and positive regulation of cholesterol esterification and biological process this GO :0010951 and negative regulation of endopeptidase activity and biological process this GO :0014061 and regulation of norepinephrine secretion and biological process this GO :0014068 and positive regulation of phosphatidylinositol 3-kinase signaling and biological process this GO :0014824 and artery smooth muscle contraction and biological process this GO :0014873 and response to muscle activity involved in regulation of muscle adaptation and biological process this GO :0016525 and negative regulation of angiogenesis and biological process this GO :0019229 and regulation of vasoconstriction and biological process this GO :0030162 and regulation of proteolysis and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0030308 and negative regulation of cell growth and biological process this GO :0030432 and peristalsis and biological process this GO :0031701 and angiotensin receptor binding and molecular function this GO :0031702 and type 1 angiotensin receptor binding and molecular function this GO :0031703 and type 2 angiotensin receptor binding and molecular function this GO :0032270 and positive regulation of cellular protein metabolic process and biological process this GO :0032930 and positive regulation of superoxide anion generation and biological process this GO :0033864 and positive regulation of NAD(P)H oxidase activity and biological process this GO :0034104 and negative regulation of tissue remodeling and biological process this GO :0034374 and low-density lipoprotein particle remodeling and biological process this GO :0035411 and catenin import into nucleus and biological process this GO :0035813 and regulation of renal sodium excretion and biological process this GO :0035815 and positive regulation of renal sodium excretion and biological process this GO :0040018 and positive regulation of multicellular organism growth and biological process this GO :0042127 and regulation of cell proliferation and biological process this GO :0042310 and vasoconstriction and biological process this GO :0042311 and vasodilation and biological process this GO :0042445 and hormone metabolic process and biological process this GO :0042756 and drinking behavior and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0043085 and positive regulation of catalytic activity and biological process this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0044255 and cellular lipid metabolic process and biological process this GO :0044267 and cellular protein metabolic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0045429 and positive regulation of nitric oxide biosynthetic process and biological process this GO :0045723 and positive regulation of fatty acid biosynthetic process and biological process this GO :0045742 and positive regulation of epidermal growth factor receptor signaling pathway and biological process this GO :0045777 and positive regulation of blood pressure and biological process this GO :0045893 and positive regulation of transcription, this GO :0004867 : serine-type endopeptidase inhibitor activity, this GO :0004867 : serine-type endopeptidase inhibitor activity and also this GO :0005179 : hormone activity and also this GO :0005515 : protein binding and also this GO :0008083 : growth factor activity and also this GO :0031701 : angiotensin receptor binding and also this GO :0031702 : type 1 angiotensin receptor binding and also this GO :0031703 : type 2 angiotensin receptor binding, this GO :0005179 : hormone activity, this GO :0005515 : protein binding, this GO :0008083 : growth factor activity, this GO :0031701 : angiotensin receptor binding, this GO :0031702 : type 1 angiotensin receptor binding, this GO :0031703 : type 2 angiotensin receptor binding, type 2 angiotensin receptor binding, angiotensinogen (serpin peptidase inhibitor |
| Identity: |
333 |
| Gene: |
AGT |
More about : AGT |
| Long gene name: |
angiotensinogen |
| Synonyms gene: |
SERPINA8 |
| Synonyms gene name: |
clade A, member 8 , serpin peptidase inhibitor |
| Synonyms name: |
alpha-1 antiproteinase, antitrypsin |
| Locus: |
1q42, 2 |
| Discovery year: |
1989-06-30 |
| GenBank acession: |
K02215 |
| Entrez gene record: |
183 |
| Pubmed identfication: |
6089875 24172014 |
| RefSeq identity: |
NM_000029 |
| Classification: |
Endogenous ligands Serpin peptidase inhibitors |
| Havana BLAST/BLAT: |
OTTHUMG00000037757 |