| Reacts with: |
Human |
| Source: |
proteins, Recombinants or rec |
| Description: |
Recombinant Human Mannan-Binding Lectin Serine Protease 1 is produced by our Mammalian expression system and the target gene encoding His20-Arg728 is expressed with a 6His tag at the C-terminus |
| Molecular Weight: |
68 kD, 80 |
| UniProt number: |
P48740 |
| State of the product: |
Liquid |
| Shipping conditions: |
Dry ice/ice packs |
| Formulation: |
10％Glycerol，pH8, 2 um filtered solution of 20 mM Tris, 200 mM sodium chloride, Supplied as a 0 |
| Storage recommendations: |
-20°, Please minimize freeze-thaw cycles, stable for 6 months after receipt, C, Store at < |
| Reconstitution: |
Dissolve the lyophilized protein in ddH2O, Do not mix by vortex or pipetting, It is not recommended to reconstitute to a concentration less than 100 &mu, Please aliquot the reconstituted solution to minimize freeze-thaw cycles, Always centrifuge tubes before opening, g/ml |
| Purity: |
and determined by Polyacrylamide gel electrophoresis, Greater than 95% |
| Sequence of the amino acid: |
HTVELNNMFGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYVKVETEDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAVDVDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSDNLFTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKIKVGPKVLGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSYRAAGNECPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKIPTCKIVDCRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYTCSAQGVWMNKVLGRSLPTCLPECGQPSRSLPSLVKRIIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQRRDTTVIPVSKEHVTVYLGLHDVRDKSGAVNSSAARVVLHPDFNIQNYNHDIALVQLQEPVPLGPHVMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQYVKLPVVPHAECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGGAFVIFDDLSQRWVVQGLVSWGGPEECGSKQVYGVYTKVSNYVDWVWEQMGLPQSVVEPQVERVDHHHHHH |
| Levels of endotoxin: |
11 IEU/ug, LAL test shows less than than 0 |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp |
| Group: |
recombinants |
| Gene target: |
MASP1 (C-6His), Mannan-Binding Lectin Serine Protease 1 |
| Short name: |
MASP1 (C-6His), Recombinant Mannan-Binding Lectin Serine Protease 1 |
| Technique: |
E, coli recombinant proteins are , novo advises they will be reconstituted in a buffer soluion or culture medium for cell culture, supplied as white sterile powder lyopillized, Recombinant, genetic recombinations , in Escherichia coli |
| Species: |
Humans, Human |
| Alternative name: |
mannan-binding lectin serine peptidase 1 (C4/complement component 2 activating component on Ra-reactive factor) (C-6His), sapiens Mannan-Binding Lectin Serine Protease 1, recombinant H |
| Alternative technique: |
rec |
| Alternative to gene target: |
3MC1 and CRARF and CRARF1 and MAP1 and MAp44 and MASP and MASP3 and PRSS5 and RaRF, Extracellular, MASP1 and IDBG-634626 and ENSBTAG00000012467 and 522347, MASP1 and IDBG-69257 and ENSG00000127241 and 102725441, Masp1 and IDBG-149706 and ENSMUSG00000022887 and 17174, calcium-dependent protein binding, lectin pathway and biological process this GO :0003824 and catalytic activity and molecular function this GO :0004252 and serine-type endopeptidase activity and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0006508 and proteolysis and biological process this GO :0006956 and complement activation and biological process this GO :0008233 and peptidase activity and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0045087 and innate immune response and biological process this GO :0045916 and negative regulation of complement activation and biological process this GO :0048306 and calcium-dependent protein binding and molecular function, this GO :0001867 and complement activation, this GO :0003824 : catalytic activity, this GO :0003824 : catalytic activity and also this GO :0004252 : serine-type endopeptidase activity and also this GO :0005509 : calcium ion binding and also this GO :0005515 : protein binding and also this GO :0008233 : peptidase activity and also this GO :0042803 : protein homodimerization activity and also this GO :0048306 : calcium-dependent protein binding, this GO :0004252 : serine-type endopeptidase activity, this GO :0005509 : calcium ion binding, this GO :0005515 : protein binding, this GO :0008233 : peptidase activity, this GO :0042803 : protein homodimerization activity, this GO :0048306 : calcium-dependent protein binding, 5648, mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) |
| Identity: |
6901 |
| Gene: |
MASP1 |
More about : MASP1 |
| Long gene name: |
mannan binding lectin serine peptidase 1 |
| Synonyms gene: |
CRARF PRSS5 |
| Synonyms gene name: |
mannan-binding lectin serine protease 1 (C4/C2 activating component of Ra-reactive factor) mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) |
| Synonyms: |
MASP |
| Synonyms name: |
C4/C2 activating component of Ra-reactive factor |
| Locus: |
3q27, 3 |
| Discovery year: |
1995-07-06 |
| GenBank acession: |
D28593 |
| Entrez gene record: |
5648 |
| Pubmed identfication: |
8018603 8240317 |
| RefSeq identity: |
NM_001879 |
| Classification: |
Sushi domain containing Proteases, serine |
| Havana BLAST/BLAT: |
OTTHUMG00000156461 |
| Locus Specific Databases: |
LRG_349 |