| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
RSPO1 / R-spondin-1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
Western blot: 1:1000-2000 |
| Intented use: |
This RSPO1 antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
284654 |
| Uniprot #: |
Q2MKA7 |
| Purity: |
Antigen affinity |
| Description: |
Acts as a ligand for frizzled FZD8 and LRP6, Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, Has a essential roles in ovary determination, LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, LGR5 or LGR6), May negatively regulate the TGF-beta pathway, Upon binding to LGR4-6 (LGR4, an important regulator of the Wnt signaling pathway, triggering the canonical Wnt signaling pathway to increase expression of target genes, R-spondin-1 is an activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors |
| Immunogen: |
A portion of amino acids 206-240 from the human protein was used as the immunogen for the RSPO1 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the RSPO1 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
RSPO1 / R-spondin-1 |
| Short name: |
RSPO1 Antibody / R-spondin-1 |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
RSPO1 (Antibody to) / R-spondin-1 |
| Alternative technique: |
antibodies |
| Identity: |
21679 |
| Gene: |
RSPO1 |
More about : RSPO1 |
| Long gene name: |
R-spondin 1 |
| Synonyms gene name: |
R-spondin homolog (Xenopus laevis) |
| Synonyms: |
FLJ40906 RSPONDIN |
| Locus: |
1p34, 3 |
| Discovery year: |
2005-08-08 |
| GenBank acession: |
AK098225 |
| Entrez gene record: |
284654 |
| RefSeq identity: |
NM_173640 |
| Classification: |
Endogenous ligands |
| Havana BLAST/BLAT: |
OTTHUMG00000004321 |